Protein Alignment: l(3)mbt and PHC3

• Sequence 1: NP_733209.1
• Gene: l(3)mbt
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_005247846.1
• Gene: PHC3
• HGNCID: 15682
• Length: 1011
• Species: Homo sapiens
• Alignment Length: 1238
• Identity: 220/1239 (18%)
• Similarity: 392/1239 (32%)
• Gaps: 377/1239 (30%)

  Fly   268 NHVKKLLTSPNP--SGEDKTRSTQKNNKQNTSASQL-KPVVA--------------------PKT 309
            :|...:.|.|||  |....|.|:.......||:|:: :|.::                    |.:
Human     8 DHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSS 72

  Fly   310 AMPIATEVPTADNNKMSLIKSKPVAIKAVPLPSQEAPIVPAVAPVVTSPEKVDVKPT-------- 366
            |.....::..|....:.|   ...|::...|.|.:...:.||...::| .:....||
Human    73 AAQYLQQMYAAQQQHLML---HTAALQQQHLSSSQLQSLAAVQASLSS-GRPSTSPTGSVTQQSS 133

  Fly   367 -AKPSIKTAPKPTPKPL------EMSVNGPAKEKKAPAKEQKQKTM----DKPPVVKEIAQ---- 416
             ::.||..:..|||..|      ..|.:|..          .|:||    ..|.:....||
Human   134 MSQTSINLSTSPTPAQLISRSQASSSTSGSI----------TQQTMLLGSTSPTLTASQAQMYLR 188

  Fly   417 -----HTPCG-----PKELPKLKRSKSFVSNHPASPVAN-NERRHSVAIMAKEVDVIEQPSAAIE 470
                 .||..     ..::|.:..|.|......|:.|.| ..|...:.:::...:...:.::..:
Human   189 AQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQ 253

  Fly   471 TITIEDDDESEEEQQKPEIKKTPKQNQKPEKQEAPKKKQIPMPILPAGITISTTSTAKKKAVRKN 535
            ::||..:..:....:..:...:|:.|:|.|                     |.:..::..||.:.
Human   254 SLTICHNKTTVTSSKISQRDPSPESNKKGE---------------------SPSLESRSTAVTRT 297

  Fly   536 SSVTTISSSSSDSSSYSDVEVVPTKKTEKELSMLPGISIIKAESLPLSREDFERSLRCDEQVPQT 600
            ||:..:.:    .:|||.::              |. |:||.:.:||                .:
Human   298 SSIHQLIA----PASYSPIQ--------------PH-SLIKHQQIPL----------------HS 327

  Fly   601 PPKSSSSSSSGSH-------ASEMSPPPKLADPKPSSPPAKNAKKANDHDANPSPSSKTNDFKKS 658
            ||      |..||       ..:...|..|.:.....||:::.....:|...|:||:..:.....
Human   328 PP------SKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSP 386

  Fly   659 MMQNLNMLKWRGQQPANLQNSTVRFELNEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSACV 723
            :..:.:.|.....|..:.|.|.|                         ...|....|.:.|:..:
Human   387 IQSHPSPLTVSPNQSQSAQQSVV-------------------------VSPPPPHSPSQSPTIII 426

  Fly   724 HPLLYLCQRCNFHGPAADFLAPHFCSVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAP-DLP 787
            ||              ...:.||            ..:..:.|....:.::...|...||. :||
Human   427 HP--------------QALIQPH------------PLVSSALQPGPNLQQSTANQVQATAQLNLP 465

  Fly   788 QKRQTNYKPHKSLSAIQEQLQQRQKDKPRKPFRWSEYLKSKGKDVAAPIH-----LFLNPFPISP 847
            ........|...:..:|:..                 |.|.|:.:.:|.|     |..:|.||:
Human   466 SHLPLPASPVVHIGPVQQSA-----------------LVSPGQQIVSPSHQQYSSLQSSPIPIA- 512

  Fly   848 NCFEIGMKLEAIDPENCSLFCVCSIVEVRGYRLKLSFDGYSSMYDFWVNADSQDIFPPGWCDETA 912
                        .|...|......|..:          ...||....|   ..:|...|
Human   513 ------------SPPQMSTSPPAQIPPL----------PLQSMQSLQV---QPEILSQG------ 546

  Fly   913 RVLQAPKDYNSERFSWSRYLVKTGGKAAPRALFGHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKI 977
            :||......:.|....:..||:...:..|......:|:|.|........|||||....|:....:
Human   547 QVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVGMHLNQCHLHKVFSL 611

  Fly   978 CVATVTDILDERIRVHFDGWDDCYDLWVHITSPYIHPCGWHEGR-----------QQLIVPPDYQ 1031
            .|..|.|:.:|.:.   :..|:|..:......|.:.|.....||           :|:.:|....
Human   612 KVYQVEDVCEEEMP---EESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVAS 673

  Fly  1032 KSAFIWDDYISEVGGMAASKELFTPRQPM----------EYQERMKLEVVDQRNPCLIRPATVVT 1086
            .||       |.:...:....:..|..|:          .......:..::.:.|..|....::|
Human   674 VSA-------SVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILT 731

  Fly  1087 R--KGYRVQLHLDCWPTEYYFWLEDDSPDLHPI-------GWC---------------------- 1120
            .  :|:.:|..|:.:|......|.:......|:       ..|
Human   732 HVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMED 796

  Fly  1121 ---EATSHELETPPGYLQPKSVMPCDVEGCRGFGN-------------AKRFNLNVHALRECC-P 1168
               |.|..|:::        .::.|:..|..|:.|             |||:|::      |. .
Human   797 MIAEETLEEMDS--------ELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVS------CSKK 847

  Fly  1169 YAPENWRQWRSKTVKPPRVAPENIRRGWAKKTKRACSEAKQAIKED--SQQEIVYPKVAEVVQAK 1231
            :|...|.:           .|:|...|   ...|..|....|.:|.  .|..|.||...|.:.:.
Human   848 FALSRWNR-----------KPDNQSLG---HRGRRPSGPDGAAREHILRQLPITYPSAEEDLASH 898

  Fly  1232 RKTSPCEEKVVKKQKQMQKEEDAEQVPDERSLAIARSFVKDYGPQFLPNYRLWQLNSAFKLDDVR 1296
            ..:.| .....:.::|.::|.:.|              ::|...:.:|.      ||.. |...:
Human   899 EDSVP-SAMTTRLRRQSERERERE--------------LRDVRIRKMPE------NSDL-LPVAQ 941

  Fly  1297 TNPLHWTSWDVCEYIERALDSTDIAKVIFEQDIDGRALLMLGRKELDTYLKLKVGPAVKLYSLIL 1361
            |.|..||..||..:|.......|||.....|:|||:|||:|....|.:.:.:|:|||:|:.:.|.
Human   942 TEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARIN 1006

  Fly  1362 NLR 1364
            :|:
Human  1007 SLK 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	MBT	822..918	CDD:214723	19/101 (19%)
		MBT	929..1028	CDD:214723	24/110 (22%)
		MBT	1038..1130	CDD:214723	16/136 (12%)
		SAM_PNT	1279..1366	CDD:280377	30/87 (34%)
PHC3	XP_005247846.1	SAM_Ph1,2,3	942..1010	CDD:188976	26/69 (38%)
		SAM	944..1011	CDD:197735	25/67 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR12247
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100