Protein Alignment l(3)mbt and scml2

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_012812742.2
• Gene: scml2 / 780057
• XenbaseID: XB-GENE-6043728
• Length: 706
• Species: Xenopus tropicalis
• Alignment Length: 752
• Identity: 166/752 - (22%)
• Similarity: 253/752 - (33%)
• Gaps: 260/752 - (34%)

  Fly   807 LQQRQKDKPRKPFRWSEYLKSKGKDVAAPIHLFLNPFPISPNCFEIGMKLEAIDPENCSLFCVCS 871
            ::...|...::.|.|.:||...| .||||.:.|........|.|::||||||.||.|.:..|:.:
 Frog     2 MKSNTKKTAKEKFNWDDYLNQVG-SVAAPPNCFKQSRTPPSNDFKVGMKLEAHDPRNITSICIAT 65

  Fly   872 IVEVRGYRLKLSFDGYSSMYDFWVNADSQDIFPPGWCDETARVLQAPKDYNSERFSWSRYLVKT- 935
            :|.:.|.||:|..||.....|||...||.||...|.|::...:||.|..:.....||..:|:||
 Frog    66 VVGITGARLRLRLDGSDDKNDFWRLVDSCDIQQIGTCEKKGDMLQPPLGFRMNASSWPMFLLKTL 130

  Fly   936 -GGKAAPRALFGHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKICVATVTDILDERIRVHFDGWDD 999
             |...||...|   ..:.|...::.|..||.|||.|..:...||.||:.|:..:.|.:.||||..
 Frog   131 NGADMAPITCF---KQEPQKPSQSFFKTGMKLEAVDKKNPYLICPATIGDVKGDDIFITFDGWRG 192

  Fly  1000 CYDLWVHITSPYIHPCGWHEGRQQLIVPPDYQKS---------AFIWDDYISEVGGMAASKELFT 1055
            .:|.|....|..|.|.||.......:.||....|         |       |.:.|:..|.:  :
 Frog   193 AFDYWCKYDSRDIFPIGWCSLTGDSLQPPGNSVSLPRTSSTPTA-------SPIKGVRRSMQ--S 248

  Fly  1056 PRQPMEYQERMKLEVVDQRNPCLIRPATVVTRKGYRVQLHLDCWPTEYYFWLEDDSPD------- 1113
            |::|::.|:..|    ..|:.|| ...:...|||.|.:          ...|..::|:
 Frog   249 PQKPVQAQKGRK----PMRDKCL-GQTSASPRKGKRPK----------NTTLSRNTPNAENQTKS 298

  Fly  1114 -------------------LHPIGWCEATSHE----------LETPPG----------------- 1132
                               |.|:...:..|::          |.:|..
 Frog   299 KGTGLKPGRKKETLALNSSLPPVNTSDGDSNKSQILKDGVGILGSPVAVISTVCVYVNKHGNSGP 363

  Fly  1133 YLQPKSVM---------PCD------VEGC-------------------------RGFGNAKRFN 1157
            :|..|.|:         |.:      |:.|                         ..|...|.
 Frog   364 HLDKKKVLQLPDHFGPGPVNVVLQQAVQACVDCAYYSKIVFSFLKSGHHGGEAITASFDGEKH-- 426

  Fly  1158 LNVHA------------LRECC------------PYAPENWRQW------RSKTVKPPRVAPENI 1192
             :||.            |.:.|            |::|......      ||||.|      |.|
 Frog   427 -SVHLPPVNSASFVLRFLEKLCHSLQCDNLFSSQPFSPHMGGAHSPTDYDRSKTTK------EEI 484

  Fly  1193 RRGWAKKTKRACSEA---KQAIKEDSQQEIVYPKVAEVVQAKRKTSPCEEKVVKKQKQMQKEE-- 1252
            .   .:..||.|.:.   ...:.....:..|:|..||:       ||.||..:.|.::..:|.
 Frog   485 T---DRSNKRYCQDPPPFSAPLSPKLPRSEVHPPEAEM-------SPTEENCMPKDQRFSEESMD 539

  Fly  1253 ------------------------------------------------------------DAEQV 1257
                                                                        |:.:.
 Frog   540 SALNTVNTASPATRNTTEYRNMGATSAYYRGSVQPVTATSNGAPVVRRSSSSSASNSCYYDSSRN 604

  Fly  1258 PDERSLAIARSFVKDYGPQFLPNYRLWQLNSAFKLDDVRTNPLHWTSWDVCEYIERALDSTDI-- 1320
            ..:|.:..|.|..   ||:.....|  |...:...|     |..|:..||..:::.| |...:
 Frog   605 RTQRRIEAASSTT---GPELHSTER--QTTQSLSKD-----PATWSVDDVMCFVKEA-DPQALAP 658

  Fly  1321 -AKVIFEQDIDGRALLMLGRKELDTYLKLKVGPAVKL 1356
             |::....:|||.|||:|....:..|:.||:|||:||
 Frog   659 HAELFRRHEIDGTALLLLRSDMIMKYMGLKLGPALKL 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	39/100 (39%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	29/96 (30%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	16/107 (15%)
		SAM_PNT	1278..1367	CDD:460486	25/82 (30%)
scml2	XP_012812742.2	MBT	14..143	CDD:459242	50/132 (38%)
		MBT_SCML2_rpt2	148..224	CDD:439099	26/75 (35%)
		RBR	255..316	CDD:465382	11/75 (15%)
		SLED	350..459	CDD:463469	12/111 (11%)
		SAM_Scm	633..704	CDD:188977	23/69 (33%)