Protein Alignment l(3)mbt and l3mbtl2

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: NP_956326.1
• Gene: l3mbtl2 / 568473
• ZFINID: ZDB-GENE-030131-8713
• Length: 805
• Species: Danio rerio
• Alignment Length: 725
• Identity: 161/725 - (22%)
• Similarity: 268/725 - (36%)
• Gaps: 215/725 - (29%)

  Fly   686 NEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSACVHPLLYLCQRCNFHGPAADFLA--PHFC 748
            |:.||....:     .||.             :||:.|...:..|:.|...|....|.:  ..||
Zfish   142 NQHNFSDDGD-----NGPV-------------KPSSWVDDGIVACEMCGAVGSIDTFFSRTKRFC 188

  Fly   749 SVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAPDLPQKRQTN-YKPHKSLSAIQEQLQQRQK 812
            |..|     .|....:::|.|.::|.|...:..::..|..|.||. .:|        :.::|.|:
Zfish   189 SASC-----SRSYSSNSKKSSILARLQGRPSKKSSHKLCPKTQTEVLRP--------KVIEQHQE 240

  Fly   813 DKP------RKPFRWSEYLKSKGKDVAAPIHLFLNPFPISPNCFE-----IGMKLEAIDPENC-- 864
            .:|      ...|.|..||:..|. :|||:..|.:    .|.|.:     :|:|:|.::....
Zfish   241 SRPFVQDATLAGFDWGSYLEKSGL-LAAPVSCFRH----VPLCAQWEDVYVGLKVEVLNTHTALP 300

  Fly   865 -SLFCVCSIVEVRGYRLKLSFDGY--SSMYDFWVNADSQDIFPPGWCDETARVLQAPKDYNSERF 926
             .::.:.::|::.||:..|.::|:  ...:|.|.|..:.|:.|.|||....:.|..|::.:.:
Zfish   301 SKVYWIATVVQLAGYKALLRYEGFEDDDRHDLWCNLGTADVHPIGWCAVNNKPLVPPQEVHQQ-- 363

  Fly   927 SWSRYLVK--TGGKAAP---------------------------------------------RAL 944
            .|..||::  .|....|                                             |.|
Zfish   364 DWKSYLMERLVGAHTIPVDFHVKMADSLRCPFRQGVRVEVVDRSQVSRTRLAVVDTVIGGRLRLL 428

  Fly   945 F------------------------GHLNMQQQMD---------VRNG----------------- 959
            :                        .|:...:.:|         |..|
Zfish   429 YEDAGLGPSGEVLSDFWCHMQSPLVHHVGWSETVDHSIKETDTNVNMGSHPAFRRVHQNSVPDQF 493

  Fly   960 ------------FAVGMHLEAEDLNDTGKICVATVTDI-LDERIRVHFDG--------WDDCYDL 1003
                        |..||.:||.|..:.|.||||:|..: ||..|.|..||        | .||
Zfish   494 KKLRTVYMGATFFKEGMKIEAIDPLNLGNICVASVRKVLLDGYIMVGIDGVEIGDGSDW-FCY-- 555

  Fly  1004 WVHITSPYIHPCGWHEGRQ-QLIVPPDYQKSAFIWDDYISEVGGMAASKELF-TPRQPMEYQERM 1066
              |.:|..|.|.|:.|... .|.|||.|.::.|.|..|:.|.|.:||.:.|| |......:...|
Zfish   556 --HASSHAILPVGYCENNDIPLTVPPGYDQATFTWPVYLEETGAVAAPQRLFNTDDVGHGFTSGM 618

  Fly  1067 KLEVVDQRNPCLIRPATVVTRKGYRVQLHLDCWPTEYYFWLEDDSPDLHPIGWCEATSHELETPP 1131
            |||.||...|.|:..|||....|..:.||.|.|..|:..|::..||:::|:||||.|.::|:.|.
Zfish   619 KLEAVDLMEPRLVCVATVRRCVGRLLLLHFDGWEPEFDQWVDCQSPEIYPVGWCEITGYQLQPPI 683

  Fly  1132 GYLQPKSVMPCDVEGCRGFGNAKRFNLNVHALRECCPYAPENWRQWRSKTVKPPRVAPENIRRGW 1196
            |...|:.                  ..:.||.::..|:..:..|::..|..|.......|.....
Zfish   684 GPEPPQG------------------QEHSHASKKAKPFKGKRKRRFLRKNAKINLKTQTNENTEM 730

  Fly  1197 AKKTKRACSEAKQA---IKEDSQQEIVYPKVAEVVQAKRKTSPCEEKVVKKQK--------QMQK 1250
            .:..:.|.:..|.:   ||.:.::|:    :|..|:.:...:|.......|:.        :.:|
Zfish   731 IQSQEAANTSDKPSTLQIKTEPEEEV----IAVRVKVEELETPILSSAQSKESHQGALTTFKREK 791

  Fly  1251 EEDAEQVPDE 1260
            ::|.::..||
Zfish   792 DDDEDEEEDE 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	26/155 (17%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	37/126 (29%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	27/71 (38%)
		SAM_PNT	1278..1367	CDD:460486
l3mbtl2	NP_956326.1	THAP	5..89	CDD:461662
		MBT_L3MBTL2_rpt1	281..380	CDD:439111	22/100 (22%)
		MBT	382..471	CDD:459242	4/88 (5%)
		MBT_L3MBTL2_rpt3	506..596	CDD:439117	36/94 (38%)
		MBT_dSfmbt-like_rpt4	612..682	CDD:439090	27/69 (39%)