Protein Alignment l(3)mbt and mbtd1

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_005169539.3
• Gene: mbtd1 / 568340
• ZFINID: ZDB-GENE-060810-138
• Length: 705
• Species: Danio rerio
• Alignment Length: 763
• Identity: 177/763 - (23%)
• Similarity: 280/763 - (36%)
• Gaps: 235/763 - (30%)

  Fly   617 MSPPPKLADPKPSSPPAKNAKKAND------------HDANPSPSSK-TNDFKKSMMQNLNMLKW 668
            |..|..:|:..|     ::.:|..|            .|::.|.||: :.|...|:..:|.::|.
Zfish     1 MENPRDMAEHTP-----RSERKRRDSFGMFDGYDSCSEDSSSSSSSEDSEDEVPSIPASLPIIKN 60

  Fly   669 RGQQPANLQNSTVRFELNEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSACVHPLLYLCQRC 733
            .||                                       :|..|..:..      :..|:.|
Zfish    61 NGQ---------------------------------------VYTYPDGKAG------MATCEMC 80

  Fly   734 NFHGPAADFLA--PHFCSVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAPDLPQKRQTNYKP 796
            ...|....|.:  ..||||.|     .|....:::|.|.::|.|      ..|...:.:....:|
Zfish    81 GMVGVRDAFYSKTKRFCSVSC-----SRSYSSNSKKASILARLQ------GKPPTKKAKVLQKQP 134

  Fly   797 HKSLSAIQEQLQQRQKDK-------PRKPFRWSEYLKSKGKDVAAPIHLFLN-PFPISPNCFEIG 853
            ..:..|...|.|..|:::       |.:.|.|.:|:.|... |.||:..|.: |..:.......|
Zfish   135 LMAKLAAYAQYQASQQNQAKSKSVVPVEGFDWGQYICSNNL-VGAPVSCFKHVPMGMCWGDIAEG 198

  Fly   854 MKLEAIDPE---NCSLFCVCSIVEVRGYRLKLSFDGY--SSMYDFWVNADSQDIFPPGWCDETAR 913
            :::|..:.:   :..::.|..||::.|::..|.::|:  .|..|||.|....:|.|.|||..:.:
Zfish   199 LRVEVFNSDTNLSTKVYWVAEIVKLAGFKALLRYEGFDNDSSRDFWCNLCIPEIHPVGWCASSGK 263

  Fly   914 VLQAPKDYNSERFSWSRYLVK--TGGKAAP----------------------------------- 941
            .|..||....:..:|..:|||  ||.|..|
Zfish   264 PLVPPKSIQHKYSNWKAFLVKRLTGAKTLPPEFATKVQENMQYPFKKLMRVEVVDKTHLCRTRVA 328

  Fly   942 ---RALFGHLNM-------------------------------------------QQQMDV---- 956
               :.:.|.|.:                                           :.|||.
Zfish   329 LVEQVIGGRLRLVYEESQDGTDDFWCHMLSPLIHSIGWSRSIGHRFKRSEVSKKIEGQMDAPSQL 393

  Fly   957 --------RNG--FAVGMHLEAEDLNDTGKICVATVTDIL-DERIRVHFDG--------WDDCYD 1002
                    :||  |..||.|||.|..:...||||||..:| |..:.:..||        | .||
Zfish   394 FLKIKDVDQNGDWFKDGMKLEAIDPLNLSAICVATVRKVLADGYLMIGIDGSEAADGSDW-FCY- 456

  Fly  1003 LWVHITSPYIHPCGWHEGRQQLIVPP-DYQKSAFIWDDYISEVGGMAASKELFTPRQPME-YQER 1065
               |.|||.|.|.|:.|.....:.|| ...|..|.|.||:.|:|.:||..:||....|.. ::..
Zfish   457 ---HSTSPSIFPVGFCEINSIELTPPRGCTKLPFKWFDYLREIGSIAAPVKLFNKDVPNHGFRVG 518

  Fly  1066 MKLEVVDQRNPCLIRPATVVTRKGYR-VQLHLDCWPTEYYFWLEDDSPDLHPIGWCEATSHELET 1129
            ||||.||...|.|:..|| |||..:| :::|.|.|..||..|::.:||||:|||||:.|.::|:.
Zfish   519 MKLEAVDLMEPRLVCVAT-VTRIVHRLLRIHFDGWEDEYDQWVDCESPDLYPIGWCQLTGYQLQP 582

  Fly  1130 PPGYL---QPKSVMPCDVEGCRGFGNAKRFNLNV--------HALRECC-----PYAPENWRQWR 1178
            |....   .|.:|.....:..:..|..|:..:.|        ..||...     ...|.::....
Zfish   583 PAAQTTREAPPNVSKQKKKAAQYKGQKKKRKIPVGRRPIGLGGPLRRRSFSGDEEQTPPHYLSHF 647

  Fly  1179 SKTVKPPRVAPENIRRGWAKKTKRACSEAKQAIKEDSQQEIVYPKVAE 1226
            |.:.:||....|        :.:...|||...:||::      |::.|
Zfish   648 SGSRRPPASGVE--------RDRSLNSEASLQVKEET------PEIDE 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	29/143 (20%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	38/99 (38%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	32/73 (44%)
		SAM_PNT	1278..1367	CDD:460486
mbtd1	XP_005169539.3	None