Protein Alignment: l(3)mbt and MBTD1

• Sequence 1: NP_733209.1
• Gene: l(3)mbt
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_011523224.1
• Gene: MBTD1
• HGNCID: 19866
• Length: 717
• Species: Homo sapiens
• Alignment Length: 845
• Identity: 187/846 (22%)
• Similarity: 274/846 (32%)
• Gaps: 327/846 (39%)

  Fly   593 CDEQVPQTPPKSSSSSSSGSHASEMSPPPKLADPKPSSPPAKNAKKANDHDANPSPSSKTNDFKK 657
            |.|.       :||||||.....|::|.|
Human    31 CSED-------TSSSSSSEESEEEVAPLP------------------------------------ 52

  Fly   658 SMMQNLNMLKWRGQQPANLQNSTVRFELNEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSAC 722
               .||.::|..||                                       :|..|..:..
Human    53 ---SNLPIIKNNGQ---------------------------------------VYTYPDGKSG-- 73

  Fly   723 VHPLLYLCQRCNFHGPAADFLA--PHFCSVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAPD 785
                :..|:.|...|....|.:  ..||||.|     .|....:::|.|.::|.|:
Human    74 ----MATCEMCGMVGVRDAFYSKTKRFCSVSC-----SRSYSSNSKKASILARLQV--------- 120

  Fly   786 LPQKRQTNYKPHKSLSAIQEQ---------------LQQRQKDK---PRKPFRWSEYLKSKGKDV 832
                  |...|.|....:|:|               ||.:.|.|   ..:.|.|..|:.| ...:
Human   121 ------TGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVSMEGFSWGNYINS-NSFI 178

  Fly   833 AAPIHLFLNPFPISPNCFEIGMKLEAIDPE-NCSL----FCVCSIVEVRGYRLKLSFDGY--SSM 890
            |||:..|.:. |:.....:|...:....|. :|||    |.:..||::.||...|.::|:  .|.
Human   179 AAPVTCFKHA-PMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSG 242

  Fly   891 YDFWVNADSQDIFPPGWCDETARVLQAPKDYNSERFSWSRYLVK--TGGKAAP------------ 941
            .|||.|....||.|.|||..:.:.|..|:....:..:|..:|||  ||.|..|
Human   243 LDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQ 307

  Fly   942 ----------------------------------------------------RALFGHLNMQQQM 954
                                                                ..|..|:...:.:
Human   308 YPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSI 372

  Fly   955 DVR-------------------------------NGFAVGMHLEAEDLNDTGKICVATVTDIL-D 987
            ..|                               ..|..||.|||.|..:...|||||:..:| |
Human   373 GHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLAD 437

  Fly   988 ERIRVHFDG--------WDDCYDLWVHITSPYIHPCGWHEGRQQLIVPP-DYQKSAFIWDDYISE 1043
            ..:.:..||        | .||    |.|||.|.|.|:.|.....:.|| .|.|..|.|.||:.|
Human   438 GFLMIGIDGSEAADGSDW-FCY----HATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRE 497

  Fly  1044 VGGMAASKELFTPRQPME-YQERMKLEVVDQRNPCLIRPATVVTRKGYR-VQLHLDCWPTEYYFW 1106
            .|.:||..:||....|.. ::..||||.||...|.||..|| |||..:| :::|.|.|..||..|
Human   498 TGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVAT-VTRIIHRLLRIHFDGWEEEYDQW 561

  Fly  1107 LEDDSPDLHPIGWCEATSHELETPPGYLQPKSVMPCDVEGCRGFGNAKRFNLNVHALRECCPYAP 1171
            ::.:||||:|:|||:.|.::|:.|                                       |.
Human   562 VDCESPDLYPVGWCQLTGYQLQPP---------------------------------------AS 587

  Fly  1172 ENWRQWRSKTVKPPRVAPENIRRGWAKKTKRACSEAKQAI----------KEDSQQEIVYPKVAE 1226
            ::.|:.:|.:.|..:.|.....:|..||.|....:...::          :..|..|.:.|....
Human   588 QSSRENQSASSKQKKKAKSQQYKGHKKKRKMPIGKKPVSLSSLPMTGGVRRSFSGDEELTPPPYR 652

  Fly  1227 VVQAK------------RKTSPCEEKVVKKQKQMQKEE--DAEQ------VPDERSLAIARSFVK 1271
            .:.|:            |:.||..:.|...|   .|||  |.|.      ..|:.|...|..::|
Human   653 TLPAQTAPEAFPPPSTSREFSPSLKTVTTLQ---LKEELLDGEDYNFLQGASDQESNGSANFYIK 714

  Fly  1272  1271
            Human   715  714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	MBT	822..918	CDD:214723	31/103 (30%)
		MBT	929..1028	CDD:214723	38/205 (19%)
		MBT	1038..1130	CDD:214723	40/94 (43%)
		SAM_PNT	1279..1366	CDD:280377
MBTD1	XP_011523224.1	MBT	170..270	CDD:214723	31/102 (30%)
		MBT	287..377	CDD:214723	7/90 (8%)
		MBT	384..481	CDD:214723	28/102 (27%)
		MBT	493..585	CDD:214723	40/93 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3766
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900