Protein Alignment l(3)mbt and L3mbtl2

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_008763933.1
• Gene: L3mbtl2 / 300320
• RGDID: 1308569
• Length: 728
• Species: Rattus norvegicus
• Alignment Length: 744
• Identity: 154/744 - (20%)
• Similarity: 262/744 - (35%)
• Gaps: 241/744 - (32%)

  Fly   621 PKLADPKPSSPPAKNAKKANDHDA------------NPSPSSKTNDFKKSMMQNLNMLKWRGQQP 673
            |:..:..|||.|   .::..|.|.            |.|..|:::.:.:...:..|..:..|:.|
  Rat     4 PRGTEETPSSEP---MEEEEDDDLELFGGYDSFRSYNSSAGSESSSYLEESSEAENEDREAGELP 65

  Fly   674 ANLQNSTVRFELNEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSACVHPLLYLCQRCNFHGP 738
                  |....|    |...|.|.              .|..|..|:        :|:.|...|.
  Rat    66 ------TSPLHL----FSSANNRA--------------LDGSGSEPA--------VCEMCGIVGT 98

  Fly   739 AADFLA--PHFCSVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAPDLPQKRQTNYKPHKS-- 799
            ...|.:  ..||||.|     .|....:::|.|.::|.|     |..|  .:|.:..:|...|
  Rat    99 REAFFSKTKRFCSVSC-----SRSYSSNSKKASILARLQ-----GKPP--TKKAKVLHKAAWSAK 151

  Fly   800 LSAIQEQLQQRQ--------KDKPRKPFRWSEYLKSKGKDVAAPIHLFLNPFPISPNCFEI--GM 854
            :.|........|        :|.....|.|.::||..... |||:..|.: .|:.....::  ||
  Rat   152 IGAFLHAQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYK-AAPVGCFKH-VPLYDQWEDVMKGM 214

  Fly   855 KLEAIDPE---NCSLFCVCSIVEVRGYRLKLSFDGY--SSMYDFWVNADSQDIFPPGWCDETARV 914
            |:|.::.:   ...::.:.::::..|||:.|.::|:  .:.:|||.|..:.|:.|.|||...:::
  Rat   215 KVEVLNSDAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKI 279

  Fly   915 LQAPKDYNSERFSWSRYLVK--TGGKAAPRALFGHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKI 977
            |..|:..:::...|..||:|  .|.:..|...  |:.|.:.|  :..|..||.||..|.....:.
  Rat   280 LVPPRTIHAKFTDWKSYLMKRLVGSRTLPADF--HIKMVESM--KYPFRQGMRLEVVDKTQVSRT 340

  Fly   978 CVATVTDILDERIRVHFDGWDDCYDLWVHITSPYIHPCGW------------------------- 1017
            .:|.|..::..|:|:.::..|...|.|.|:.||.|||.||
  Rat   341 RMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRCDMSHHPTFRK 405

  Fly  1018 -----------------------HEGRQ------------------------------------- 1022
                                   .||.:
  Rat   406 IYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATICKVLLDGYLMICVDGGPSTD 470

  Fly  1023 -------------------------QLIVPPDYQKSAFIWDDYISEVGGMAASKELFTPRQPME- 1061
                                     :|..|..|:...|.|:.|:.:....||...||....|..
  Rat   471 GSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFDWESYLEKTKSKAAPARLFNMDCPNHG 535

  Fly  1062 YQERMKLEVVDQRNPCLIRPATVVTRKGYRVQLHLDCWPTEYYFWLEDDSPDLHPIGWCEATSHE 1126
            ::..||||.||...|.||..|||.......:.:|.|.|..||..|::.:|||::|:||||.|.::
  Rat   536 FKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNEYDQWVDCESPDIYPVGWCELTGYQ 600

  Fly  1127 LETPPGYLQPKSVMPCDVEGCRGFGNAKRFNLNVHALRECCPYAPENWRQWRSKTVKPPRVAPEN 1191
            |: ||...:|.:                                |:..:.           |.:.
  Rat   601 LQ-PPVSAEPNT--------------------------------PQKGKD-----------ATKK 621

  Fly  1192 IRRGWAKKTKRACSEAKQAIKEDSQQEIV 1220
            .::.:.||.||..|...:.:::.|::.::
  Rat   622 KKKQFGKKRKRIPSAKTRPLRQSSKKPLL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	26/107 (24%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	29/197 (15%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	29/72 (40%)
		SAM_PNT	1278..1367	CDD:460486
L3mbtl2	XP_008763933.1	MBT_L3MBTL2_rpt1	207..308	CDD:439111	25/100 (25%)
		MBT_L3MBTL2_rpt2	310..393	CDD:439114	24/86 (28%)
		MBT_L3MBTL2_rpt3	428..518	CDD:439117	8/89 (9%)
		MBT_dSfmbt-like_rpt4	534..604	CDD:439090	28/70 (40%)