Protein Alignment: l(3)mbt and SCML2

• Sequence 1: NP_733209.1
• Gene: l(3)mbt
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: NP_006080.1
• Gene: SCML2
• HGNCID: 10581
• Length: 700
• Species: Homo sapiens
• Alignment Length: 750
• Identity: 185/750 (25%)
• Similarity: 271/750 (36%)
• Gaps: 240/750 (32%)

  Fly   788 QKRQTNYKPHKSLSAIQEQLQQRQKDKPRKPFRWSEYLKSKGKDVAAPIHLFLNPFPISP-NCFE 851
            :|......|..|.|::|           |..|.|.||||..| .::||...| ....|.| |.|:
Human    13 KKENQEKTPQSSTSSVQ-----------RDDFHWEEYLKETG-SISAPSECF-RQSQIPPVNDFK 64

  Fly   852 IGMKLEAIDPENCSLFCVCSIVEVRGYRLKLSFDGYSSMYDFWVNADSQDIFPPGWCDETARVLQ 916
            :||||||.||.|.:..|:.:::.:.|.||:|..||..:..|||...||.||.|.|.|::...:||
Human    65 VGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQ 129

  Fly   917 APKDYNSERFSWSRYLVKT--GGKAAPRALFGHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKICV 979
            .|..|.....||..:|:||  |.:.|...||   ..:......|.|.|||.|||.|..:...||.
Human   130 PPLGYQMNTSSWPMFLLKTLNGSEMASATLF---KKEPPKPPLNNFKVGMKLEAIDKKNPYLICP 191

  Fly   980 ATVTDILDERIRVHFDGWDDCYDLWVHITSPYIHPCGWHEGRQQLIVPP---------------- 1028
            ||:.|:..:.:.:.||||...:|.|....|..|.|.||......::.||
Human   192 ATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPPGTSVPIVKNIAKTESS 256

  Fly  1029 ----------DYQKSAFIW-------DDYISEVGGMAASK-----ELFTPRQ--PMEYQERMKLE 1069
                      ..||:..|.       ...|...|..|..|     :..|||:  |...::...|.
Human   257 PSEASQHSMQSPQKTTLILPTQQVRRSSRIKPPGPTAVPKRSSSVKNITPRKKGPNSGKKEKPLP 321

  Fly  1070 VVDQRN---------------------PCLIRPATV---VTRKGYRVQLHLDCWPTEYYFWLEDD 1110
            |:...:                     ||.|..:||   |.:.| ....|||  |...     ..
Human   322 VICSTSAASLKSLTRDRGMLYKDVASGPCKIVMSTVCVYVNKHG-NFGPHLD--PKRI-----QQ 378

  Fly  1111 SPDLH----PIG--------WCEATSHELETPPGYLQPKS----VMPCDVEG---------CRGF 1150
            .|| |    |:.        .|...:.|.:|..|||:|.:    |:....:|         ....
Human   379 LPD-HFGPGPVNVVLRRIVQACVDCALETKTVFGYLKPDNRGGEVITASFDGETHSIQLPPVNSA 442

  Fly  1151 GNAKRFNLN-VHALRECC-------PY------------------APENWRQWRSKTVKP----P 1185
            ..|.||..| .|:|:  |       |:                  |.|:..:.:|....|    |
Human   443 SFALRFLENFCHSLQ--CDNLLSSQPFSSSRGHTHSSAEHDKNQSAKEDVTERQSTKRSPQQTVP 505

  Fly  1186 RVAPENIRRGWAKKTKRACSEA------------KQAIKEDSQQE----------------IVYP 1222
            .|.|.:.:   ..|||...||.            ::.:.|||:..                .::.
Human   506 YVVPLSPK---LPKTKEYASEGEPLFAGGSAIPKEENLSEDSKSSSLNSGNYLNPACRNPMYIHT 567

  Fly  1223 KVAE--------------VVQAKRKTSPCEEKVVKKQKQMQKEEDAEQ---VPDERSLAIARSFV 1270
            .|::              |.....|:||.|.|.     |||::.:|..   |||..  .:.:.|.
Human   568 SVSQDFSRSVPGTTSSPLVGDISPKSSPHEVKF-----QMQRKSEAPSYIAVPDPS--VLKQGFS 625

  Fly  1271 KDYGPQFLPNYRLWQLNSAFKLDDVRTNPLHWTSWDVCEYIERALDSTD------IAKVIFEQDI 1329
            ||                          |..|:..:|.::::.    ||      :|.:..:.:|
Human   626 KD--------------------------PSTWSVDEVIQFMKH----TDPQISGPLADLFRQHEI 660

  Fly  1330 DGRALLMLGRKELDTYLKLKVGPAVKLYSLILNLR 1364
            ||:||.:|....:..|:.||:|||:||...|..|:
Human   661 DGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLK 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	MBT	822..918	CDD:214723	40/97 (41%)
		MBT	929..1028	CDD:214723	33/101 (33%)
		MBT	1038..1130	CDD:214723	28/135 (21%)
		SAM_PNT	1279..1366	CDD:280377	22/92 (24%)
SCML2	NP_006080.1	MBT 1	33..131		42/100 (42%)
		MBT	36..131	CDD:214723	40/97 (41%)
		MBT 2	139..240		35/104 (34%)
		MBT	142..240	CDD:214723	33/101 (33%)
		DUF3588	356..465	CDD:288954	28/120 (23%)
		SAM_Scm	625..696	CDD:188977	24/101 (24%)
		SAM	628..696	CDD:197735	22/72 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C87426167
eggNOG	1	0.900				E1_KOG3766
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.750	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740