DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)mbt and samd7

DIOPT Version :9

Sequence 1:	NP_733209.1	Gene:	l(3)mbt / 43288	FlyBaseID:	FBgn0002441	Length:	1477	Species:	Drosophila melanogaster
Sequence 2:	XP_004914482.1	Gene:	samd7 / 100496820	XenbaseID:	XB-GENE-948462	Length:	534	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	107/507 - (21%)
Similarity:	185/507 - (36%)	Gaps:	137/507 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1005 VHITSPYIHPCGWHEG--RQQLIVPPDYQKSAFIWDDYISEVGGMAASKELFTPRQPMEYQERMK 1067
            :|:.|.:.|....|.|  ..::...|.|   .|:..|.:..|   |..:||.....    ..||:
Frog    94 LHVASQFGHSLPAHTGILSNRVFSSPGY---GFLQTDPMDFV---ARRQELLQKHN----MNRME 148

  Fly  1068 LEVVDQRNPCLIRPATVVTRKGYRVQLHLDCWPTEYYFWLEDDSPDL-HPIGWCEATSHELETPP 1131
            || ::...|.  |......|||:.                :.::|.| |.|     :|:.:....
Frog   149 LE-MNAMYPA--RDIDKSQRKGFN----------------DLEAPFLFHGI-----SSNPMAVRG 189

  Fly  1132 GYLQPKSVMPCDVEGCRGFGNAKRF-NLNVHA-LRECCPYAPENWRQWRSKTVKPPRVAPENIRR 1194
            ..:.|:..:|.||     |.:...| :|:.|| |:...|| |......|.:..:|.|      |.
Frog   190 RQMVPEGHLPSDV-----FVHRNAFESLHGHAMLKTASPY-PSMSNLQRERARRPGR------RA 242

  Fly  1195 GWAKKT------------KRACSEAKQAIKEDSQQEIVYPKVAEVVQAKRKTSPCEEKVVKKQKQ 1247
            |..|.|            |.....|....::|.:::.....:::..|.|.:..|..:|...:.:.
Frog   243 GNQKATDHMGVAKIQADNKPPSPPAPTDEEKDEKKDEETGTMSKCDQIKTEVQPALDKSSSELQD 307

  Fly  1248 MQKEEDAEQVPDERSLAIARSFVKDYGPQ-----FLPNYRLWQ---------------LNSAF-- 1290
            .||..: :.:|  |.:|..||.: |.||.     |...| ::|               :||..
Frog   308 PQKMSN-QNIP--REIANGRSEM-DKGPNNTGTAFEERY-IYQPPVHLSATPYSFPVAMNSPLLP 367

  Fly  1291 -------------KLDDVRTNPLHWTSWDVCEYIERALDSTDIAKVIFEQDIDGRALLMLGRKEL 1342
                         .::|:|    .|.|.||..:|......:..|:|..:.||||..|.:|..:.|
Frog   368 GTQGLFLTREDLPSVEDIR----KWNSQDVYNFILNLPGCSSYAQVFKDHDIDGLTLPLLTEEHL 428

  Fly  1343 DTYLKLKVGPAVKLYSLILNLRIAVVCK----FDSKNIELESNTAGPIQREMDTPVSAIKQLPEQ 1403
            ...:.||:|||:|       :|..::|:    |...:::|..:.:.......:.|...:..||
Frog   429 LDTMGLKLGPALK-------IRSQIICRLGNIFHMPSLQLTGSISSTAPMPPEHPSEVVSPLP-- 484

  Fly  1404 SQTNGYKTDHDQELSESGDDDDDEDVMLDSDDFLSVKPSCLVIDEDADGDGD 1455
                  .|::...|...|..|.|           .:||..:::.|:.:...|
Frog   485 ------CTNNSDILPSPGPQDQD-----------PLKPGEIIMSENKENPCD 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	MBT	822..918	CDD:214723
		MBT	929..1028	CDD:214723	5/24 (21%)
		MBT	1038..1130	CDD:214723	19/92 (21%)
		SAM_PNT	1279..1366	CDD:280377	27/116 (23%)
samd7	XP_004914482.1	SAM_Samd7,11	385..452	CDD:188978	23/77 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910