Protein Alignment l(3)mbt and l3mbtl1

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_031750143.1
• Gene: l3mbtl1 / 100495734
• XenbaseID: XB-GENE-949999
• Length: 757
• Species: Xenopus tropicalis
• Alignment Length: 875
• Identity: 263/875 - (30%)
• Similarity: 389/875 - (44%)
• Gaps: 195/875 - (22%)

  Fly   554 VEVVPTK-KTEKELSMLPGISIIKAESLPLSREDFERSLRCDEQVPQTPPKSSSSSSSGSHASEM 617
            ::::.|| |:|.|:|...|....:...|..|.:        .:.|.|.||         :.:|||
 Frog     1 MDLIVTKAKSEPEISAPSGKVTSEGTGLLASSQ--------TQAVVQLPP---------AFSSEM 48

  Fly   618 SPPPKLADPKPSSPPAKNAKKANDHDANPSPSSKTNDFKKSMMQNLNMLKWRGQQ---PANLQNS 679
            ..|.::  .|..:.|.|.|..|.              |.         .:|...|   |.:.|::
 Frog    49 QHPQQM--EKKGAEPVKVAVNAR--------------FP---------FRWSEPQEGIPRSPQDN 88

  Fly   680 TVRFELNEFNFLQINERCQPRQGPAAYFERPLYDRPGRRPSACVHPLLYLCQRCNFHGPAADFLA 744
            .:  |:.|.::...::..:.|.|........|.|..|     |.|.:...|:.|   |....|..
 Frog    89 PI--EVQETDYQTSSQDAEGRTGSPTDSGLSLCDTCG-----CRHMVGGTCETC---GDICGFKE 143

  Fly   745 PHFC------------SVGCVRRSQKRRLPQSTQK--ESKISRTQLEQTAGTAPDLPQKRQTNYK 795
            ...|            ..|...:..|:|.|:..|.  ||:...||.|          ||...:.:
 Frog   144 SVHCRSLVMETSLVFGGGGETPKPVKKRRPKEYQSPAESEAEFTQKE----------QKSTGHIE 198

  Fly   796 PHKSLSAIQEQLQQR----QKDKPRKPFRWSEYLKSKGKDVAAPIHLFLNPFPIS---PNCFEIG 853
            ...:.|.::|:..||    ..|:..:|:.||.|| .:.|.:|||::|| ..:.:.   .|.|::|
 Frog   199 ESLARSCVKEEWSQRDIRVSGDELGEPWSWSTYL-DELKCIAAPLNLF-REWQLGAQHKNSFKVG 261

  Fly   854 MKLEAIDPENCSLFCVCSIVEVRGYRLKLSFDGYSSMYDFWVNADSQDIFPPGWCDETARVLQAP 918
            ||||.|||::.||:.:.::.||.|:|::|.|||||..:||||||||.||.|.|||:.|...||.|
 Frog   262 MKLEGIDPQHPSLYFILTVTEVCGFRIRLHFDGYSDCHDFWVNADSPDIHPAGWCERTGHKLQPP 326

  Fly   919 KDYNSERFSWSRYLVKTGGKAAPRALFGHLNMQQQMDVRNG-----FAVGMHLEAEDLNDTGKIC 978
            |.|..|.|||:.||.:|....||:.||        :..:.|     |.|||.|||.|..:...||
 Frog   327 KGYKDEDFSWTNYLRQTKAPVAPKHLF--------VTPKIGAPPSLFRVGMKLEAVDRMNPSLIC 383

  Fly   979 VATVTDILDERIRVHFDGWDDCYDLWVHITSPYIHPCGWHEGRQQLIVPP-DY-QKSAFIWDDYI 1041
            ||:|||::::|..||||.|.|.||.|...:|||:||.||.|..::::.|| || ....|.|..|:
 Frog   384 VASVTDVIEDRFLVHFDNWGDTYDYWCDPSSPYVHPVGWCEQHEKILTPPQDYPDPEGFSWGKYL 448

  Fly  1042 SEVGGMAASKELFTPRQPMEYQERMKLEVVDQRNPCLIRPATVVTRKGYRVQLHLDCWPTEYYFW 1106
            ||...:|...:.|.||.|..::..|:||.||:|:|.||..|:||..:.:|:::|.|.|...|.||
 Frog   449 SETKTVAVPAQAFHPRPPHGFKVDMRLEAVDRRSPSLICVASVVEVEEFRIKVHFDGWSHMYDFW 513

  Fly  1107 LEDDSPDLHPIGWCEATSHELETP----------PG-----------------Y-LQPKSVMPCD 1143
            |:.|.|||||.||.:.|.|.|:||          ||                 | ||.:.   |.
 Frog   514 LDADHPDLHPAGWSQRTGHPLQTPLRCRDVSNMSPGPCVSLSCKEMSHTRNNKYGLQHRK---CP 575

  Fly  1144 VEGCRGFGNAK-RFNLNVHALRECCPYAPENWRQWRSKTVKP---PRVAPENIRRGWAKKTKRAC 1204
            ..||.|.|:.. ||  ..|.....||.|..|....||:...|   .|.:..:.|.|...|.:|
 Frog   576 TPGCDGSGHVTGRF--TAHHCLSGCPLADRNQNPTRSRNPIPFPSRRKSRHHGRIGRPPKYRR-- 636

  Fly  1205 SEAKQAIKEDSQQEIVYPKV---AEVVQAKRKTSPCEEKVVKKQKQMQKEEDAEQVPDERSLAIA 1266
                  :::||.|:.|:...   |..|...|..|.|.|:..:
 Frog   637 ------VQQDSYQDPVHQSFFMSALSVHPDRAHSHCWEQHCR----------------------- 672

  Fly  1267 RSFVKDYGPQFLPNYRLWQLNSAFKLDDVRTNPLHWTSWDVCEYIERALDSTDIAKVIFEQDIDG 1331
                      .||.......::..|          |::.:|..:::......|.|::..|:.|||
 Frog   673 ----------LLPGVAGISASTVSK----------WSTEEVFSFVQTLTGCEDQARLFREEMIDG 717

  Fly  1332 RALLMLGRKELDTYLKLKVGPAVKLYSLIL 1361
            :|||:|.:.::...|.:|:|||||:|:.||
 Frog   718 QALLLLTQTDIVKILCIKLGPAVKIYNSIL 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	51/101 (50%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	43/94 (46%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	32/71 (45%)
		SAM_PNT	1278..1367	CDD:460486	25/84 (30%)
l3mbtl1	XP_031750143.1	MBT_L3MBTL1_rpt1	245..353	CDD:439121	52/108 (48%)
		MBT	360..452	CDD:459242	42/91 (46%)
		MBT_L3MBTL1_rpt3	465..539	CDD:439127	34/73 (47%)
		zf-C2HC	573..601	CDD:460240	10/32 (31%)
		SAM_Scm-like-3MBT3,4	685..750	CDD:188981	23/73 (32%)