Protein Alignment l(3)mbt and l3mbtl1

DIOPT Version :10

• Sequence 1: NP_733209.1
• Gene: l(3)mbt / 43288
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_002666454.2
• Gene: l3mbtl1 / 100321295
• ZFINID: ZDB-GENE-090313-102
• Length: 815
• Species: Danio rerio
• Alignment Length: 884
• Identity: 248/884 - (28%)
• Similarity: 359/884 - (40%)
• Gaps: 219/884 - (24%)

  Fly   602 PKSSSSSSS--GSHASEMSPP-------PKLADPKPSSPPAKNAKKA---NDHDANPSPSSKTND 654
            |..||.|.:  .|.|..:.|.       |..|.|.|.....:||.||   ::.:|...|:.....
Zfish    17 PSESSVSHAPIDSSAHRLKPQDTTTIIFPASAHPLPKVELPQNAIKAIKGSELEATSLPAQVGGT 81

  Fly   655 FKKSMMQNLNMLKWR-------GQQ--------------------PANLQNSTVRFELNEFNFLQ 692
            .       :::|.|:       |..                    |.||.....:.:.....|.|
Zfish    82 I-------VHVLGWKEGMAILPGSNLKLCVSDTGALEVISEGKIGPTNLPTEGAQMKPANMEFKQ 139

  Fly   693 INERCQPRQG----PAAYFERPLYDRPGRR----PSACVHPLLYLCQRC--NFH-----GPAADF 742
            . |:.....|    |||:.|.   ||..|.    ..:.||      .||  |.|     |.....
Zfish   140 A-EKSDVSAGGNGRPAAFLEA---DRLHRARIEVQDSPVH------SRCGQNMHMTELRGEPMSE 194

  Fly   743 LAPHFCSVGCVRRSQKRRLPQSTQKESKISRTQLEQTAGTAPDLPQKRQTNYKP----HKSLSAI 803
            :.........:.|......|...:|..:.:.             |.:..::.:|    .::|...
Zfish   195 IPAGLAEAQVMYREHDMMKPMKKRKRREYNS-------------PSEDDSDAEPMDEKSEALKID 246

  Fly   804 QEQLQQRQKDKPRKPFRWSEYLKSKGKDVAAPIHLF--LNPFPISPNCFEIGMKLEAIDPENCSL 866
            ..|::....:...:|:.|.:||:.: |.:|||:.||  ....|:..|.|..|||||.|||::.|:
Zfish   247 GRQIKTGSAETKLEPWSWPQYLELQ-KAIAAPVRLFQETQRVPLIRNSFRQGMKLEGIDPQHPSM 310

  Fly   867 FCVCSIVEVRGYRLKLSFDGYSSMYDFWVNADSQDIFPPGWCDETARVLQAPKDYNSERFSWSRY 931
            :.|.::.||.||||:|.|||||..:||||||:..||.|.|||:.||..|..||....|.||||.|
Zfish   311 YFVLTVAEVCGYRLRLHFDGYSDCHDFWVNANCADIHPAGWCESTAHKLHTPKGCKEEEFSWSNY 375

  Fly   932 LVKTGGKAAPRALFGHLNMQQQMDVRNGFAVGMHLEAEDLNDTGKICVATVTDILDERIRVHFDG 996
            |..|..:|||:.|| ..:::.:.|.  ||.|||.|||.|..:...||||||||.:.:|..||||.
Zfish   376 LKITRSQAAPKELF-ISSVKPETDC--GFEVGMKLEAVDRMNPSLICVATVTDRVADRFLVHFDN 437

  Fly   997 WDDCYDLWVHITSPYIHPCGW-HEGRQQLIVPPDY-QKSAFIWDDYISEVGGMAASKELFTPRQP 1059
            |||.||.|...:||||||.|| ||....|..|.|| :...|.|:.|:.|.|..|.:.|.|..|..
Zfish   438 WDDTYDYWCDSSSPYIHPIGWCHERGLPLTPPQDYPEVDRFSWERYLEETGSTAVAAEAFRVRPA 502

  Fly  1060 MEYQERMKLEVVDQRNPCLIRPATVVTRKGYRVQLHLDCWPTEYYFWLEDDSPDLHPIGWCEATS 1124
            ..:|.:||||.||:|.|.|||.|||.....||:::|.|.|...|..|::.|.||:||.||||:|.
Zfish   503 HSFQVQMKLEAVDKRCPGLIRVATVQEVDTYRIKIHFDGWSHLYDEWMDSDHPDIHPAGWCESTG 567

  Fly  1125 HELETPPGYLQPKSVMP-----------------------------------CDVEGCRGFGNAK 1154
            |.|:.||  .||....|                                   |...||.|.|:..
Zfish   568 HPLKPPP--CQPTVPKPGPRESLAVRQPSFSMSCKSLPQPRNTSKYSFHHRKCPTPGCDGSGHVT 630

  Fly  1155 -RFNLNVHALRECCPYAPENW--------------------------RQWRSKTVKPPRVAPENI 1192
             ||  ..|.....||.|..|.                          .::..:..:||:
Zfish   631 GRF--TAHHCLSGCPLAERNQGRLKADLSDTEGSRRNLLVFGQRAKKSRYHGRIGRPPK------ 687

  Fly  1193 RRGWAKKTKRACSEAKQAIKEDSQQEIVYPKVAEVVQAKRKTSPCEEKVVKKQKQMQKEEDAEQV 1257
               :.|..:|.|    |::..:.....:: ..|....::|..|.|.|:..|
Zfish   688 ---YRKSQQRNC----QSMTSEGMYSSLF-MTAFTANSERTLSLCWEQHCK-------------- 730

  Fly  1258 PDERSLAIARSFVKDYGPQFLPNYRLWQLNSAFKLDDVRTNPLHWTSWDVCEYIERALDSTDIAK 1322
                               .||..      :......|.|    ||..:|..::...:...:.|:
Zfish   731 -------------------LLPGV------AGIHAGQVAT----WTIEEVFGFVNNLIGCEEQAR 766

  Fly  1323 VIFEQDIDGRALLMLGRKELDTYLKLKVGPAVKLYSLIL 1361
            :..::.|||.:.|:|.:.::...:.:|:|||:|:::.||
Zfish   767 IFKDEMIDGESFLLLTQNDIVKIMNIKLGPALKIHNAIL 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	PRK10819	<332..>427	CDD:236768
		MBT_L3MBTL1-like_rpt1	846..945	CDD:439091	52/98 (53%)
		MBT_L3MBTL1-like_rpt2	957..1045	CDD:439092	46/89 (52%)
		MBT_L3MBTL1-like_rpt3	1058..1130	CDD:439093	34/71 (48%)
		SAM_PNT	1278..1367	CDD:460486	20/84 (24%)
l3mbtl1	XP_002666454.2	MBT_L3MBTL1_rpt1	281..389	CDD:439121	54/107 (50%)
		MBT_L3MBTL1_rpt2	396..488	CDD:439124	47/93 (51%)
		MBT_L3MBTL1_rpt3	501..575	CDD:439127	36/75 (48%)
		zf-C2HC	617..645	CDD:460240	10/29 (34%)
		SAM_Scm-like-3MBT3,4	743..808	CDD:188981	18/67 (27%)