DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17991 and CG16781

DIOPT Version :9

Sequence 1:	NP_651547.1	Gene:	CG17991 / 43279	FlyBaseID:	FBgn0039498	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001259211.1	Gene:	CG16781 / 31315	FlyBaseID:	FBgn0029661	Length:	386	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	116/316 - (36%)
Similarity:	166/316 - (52%)	Gaps:	62/316 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ERCCWICFETDKEAGRQAWVNPCLCRGTNKWVHQSCISLWIDEKTRINNNLQAVSCPQCQTEYTI 84
            ||.|||||.|.::.....||.||.|||..|||||||:..||||| ::.:..|.|.|.||||||.:
  Fly    41 ERICWICFATSEDNPHAHWVQPCQCRGDTKWVHQSCLYRWIDEK-QLGDRRQTVICQQCQTEYIM 104

  Fly    85 AYPNLWIFDRALE--------LTNDLILTNLYNCLANVFTVVFAYWSAVSFGAKTYLQITGQEGH 141
            .:|.:....|.||        :...|:|.....|:         ||.|:::||.|.:|:.||: .
  Fly   105 VFPQMNPIARVLEKLDYAVRRICPFLVLGMFLCCI---------YWIALTYGAFTIIQVVGQD-R 159

  Fly   142 VHQIIQSGDLLVVLVGFPLISVVLILGRLIPWEDALLRFIRICYSLLRSLSMMCLGRK--YDHQT 204
            ..|:::  :.:::|||.|.|.|.|||.||:.|:||:|:.:|..|        :.:.||  :.|:|
  Fly   160 AMQLME--NKVILLVGLPFIPVGLILFRLVRWKDAVLKAMRSIY--------IYIPRKLPFFHRT 214

  Fly   205 E-----------------------------PYPSAP-MTE-YSASRVVCGAILLPTISMYVGRVL 238
            .                             |....| :|| :..||::|||..|||.:..||.|.
  Fly   215 NQSEGASRDLGDLGDLDDLSVSSSSSISLPPIQHNPSITEPFYISRLICGAFFLPTFATTVGNVF 279

  Fly   239 YSSVDDRLQQTLLGGLTFIAIKGFLKMYLMHSQYICRMKRRVLDYTKENLAEADGH 294
            :..:||.||:|:|||:.:|.|||.|||||....|:.|:.|.:|:||.||:...|.|
  Fly   280 FGRLDDALQRTILGGIAYIGIKGLLKMYLDQKLYLRRLGRCILNYTDENVRMIDQH 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17991	NP_651547.1	RINGv	22..79	CDD:128983	29/56 (52%)
CG16781	NP_001259211.1	RINGv	43..99	CDD:128983	29/56 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458026
Domainoid	1	1.000	47	1.000	Domainoid score	I4521
eggNOG	1	0.900	-	-		E1_KOG3053
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6573
OMA	1	1.010	-	-		QHG47732
OrthoDB	1	1.010	-	-		D426217at33208
OrthoFinder	1	1.000	-	-		FOG0003968
OrthoInspector	1	1.000	-	-		otm14746
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X270
	11	10.810