Protein Alignment Ser and LOC100535882

DIOPT Version :10

• Sequence 1: NP_524527.3
• Gene: Ser / 43275
• FlyBaseID: FBgn0004197
• Length: 1407
• Species: Drosophila melanogaster
• Sequence 2: XP_003200521.2
• Gene: LOC100535882 / 100535882
• -ID: -
• Length: 783
• Species: Danio rerio
• Alignment Length: 688
• Identity: 257/688 - (37%)
• Similarity: 336/688 - (48%)
• Gaps: 133/688 - (19%)

  Fly    60 RSLKSACNLIALILILLVHK---ISAAGNFELEILEISNTNSHLLNGYCCGMPAELRATKTIGCS 121
            |.:|...:...:.|..|..:   :.|.|.||::|.:..|....|.:|.||. |......:.....
Zfish    67 RDVKRGLHWTVICLFSLALRPQVVCAVGTFEVQIRQWQNPQGILQSGQCCD-PQSSGGQRCSSGD 130

  Fly   122 PCTTAFRLCLKEYQTTEQGASIS-TG-CSFGNATTKILGGSSFVL-------SDPGVGAIVLPFT 177
            .|.|.|:.||||||     |.:: || |::|..:|.:|||:|..|       ||...|.||:||.
Zfish   131 QCETFFKACLKEYQ-----ARVAPTGTCTYGTGSTPVLGGNSHSLHHHGNEGSDSRNGRIVIPFK 190

  Fly   178 FRWTKSFTLILQALDMYN-TSYPDAERLIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCA 241
            :.|||||:|:::|||..| ||....|.|||....|.::.|..:|::..|.||...:.||:|.:|.
Zfish   191 YAWTKSFSLVIEALDHDNETSEAGREELIERVLLSSMLNPGEQWQSFRHHGRTFTLEYRLRFRCD 255

  Fly   242 VTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECEC 306
            ..||...|...||.|||.|||:.|.:.|.|:|..||.|..|.:|:||.||...||.||.||||:|
Zfish   256 ANYYGPLCNKLCRARDDFFGHFDCDASGIKVCKEGWTGAECRQAVCKQGCHLDHGSCDLPGECKC 320

  Fly   307 RPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAP 371
            ..||:|.||:||..:|||.||:|. ..|||||||||||:|||:|||:||.|:|||:||||.||.|
Zfish   321 HYGWKGDLCDECETFPGCDHGTCT-EPWKCVCDTNWGGLLCDKDLNYCGNHQPCKNGGTCTNTEP 384

  Fly   372 DKYRCTCAEGLSGEQCEIVEHPCATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSS 436
            ::|.|.|.||..|..|:|||:.|.:.||.|||||...
Zfish   385 NEYLCVCQEGFRGRNCDIVENACLSAPCENGGTCVED---------------------------- 421

  Fly   437 MRSLDHLRPEGQALNGSSSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEH 501
                    |.|                          |:|.|:.|||||:|...:.:|...||..
Zfish   422 --------PSG--------------------------FSCRCSPGWTGPSCASAVQQCDSSPCGR 452

  Fly   502 GGTCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAA 566
            |.||.:...||:|.|||.|.|..||:|.||||.
Zfish   453 GATCQETPEGFQCLCPPFWTGRTCQLDTNECET-------------------------------- 485

  Fly   567 LTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDY 631
                        |.|:||:.|||..|.:.|.|..||.|..|......|.|.|.||..|    .|.
Zfish   486 ------------GVCVNARSCRNLIGGYLCDCLPGWSGPNCDIWNSSCRGLCLNGGHC----KDS 534

  Fly   632 RCACASGFKGRDCETDIDECATSPCRNGGECVDMVGKFN--CICPLGYSGSLCEEAKENCTPSPC 694
            :|.|..||.|:.|:..::.|.::.|.|||:||:..|...  |.|||||:|:.||...:.|.|:||
Zfish   535 QCVCLPGFSGKLCQIAVNACDSNTCVNGGQCVERQGGTGLLCRCPLGYTGTHCETELDLCNPNPC 599

  Fly   695 -LEGHCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPC 731
             .|..||:|..||.|.||....|..|..|:..|.:|.|
Zfish   600 PKEMPCLSTGGGYKCVCPEGYFGNECLNLKDPCHEPHC 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser	NP_524527.3	MNNL	83..238	CDD:462222	61/164 (37%)
		DSL	220..282	CDD:128366	26/61 (43%)
		EGF_CA	350..388	CDD:238011	22/37 (59%)
		EGF_CA	490..526	CDD:238011	14/35 (40%)
		EGF_CA	610..645	CDD:238011	12/34 (35%)
		EGF_CA	647..683	CDD:238011	15/37 (41%)
		EGF_CA	690..720	CDD:238011	13/30 (43%)
		EGF_CA	798..833	CDD:238011
		EGF_CA	879..913	CDD:238011
		EGF_CA	916..952	CDD:238011
		VWC_out	<993..1053	CDD:214565
LOC100535882	XP_003200521.2	MNNL	94..252	CDD:462222	61/163 (37%)
		DSL	234..296	CDD:473190	26/61 (43%)
		EGF_CA	363..400	CDD:238011	22/36 (61%)
		EGF_CA	405..438	CDD:238011	18/94 (19%)
		EGF_CA	446..477	CDD:238011	13/30 (43%)
		EGF_CA	479..514	CDD:238011	18/78 (23%)
		EGF_CA	551..588	CDD:238011	15/36 (42%)
		EGF	594..623	CDD:394967	13/28 (46%)