DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5909 and try-3

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001367393.1	Gene:	try-3 / 183420	WormBaseID:	WBGene00006621	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	284	Identity:	67/284 - (23%)
Similarity:	122/284 - (42%)	Gaps:	50/284 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 NSVTNCGNKGNP----KVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCI- 176
            |::..|.....|    ::.||.:...| ..|:|.|....::.:...||.::|.:..::|||||.
Worm    21 NAINLCEESYKPIFSFRIIGGNSIDDG-ANWMAKLVSYGDNGQGILCGATVIDDFWLVTAAHCAL 84

  Fly   177 -IDQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHDVAIIKL 240
             :.....:.||..:::.|                   ..:.:::..:|..|.:....:|:|::::
Worm    85 QLQTRSFVYVREPKNNRE-------------------RSFSVKEAYIHSGYNNQTADNDIALLRI 130

  Fly   241 DRVVKEKSHIKPVCLPIDQKSQELDFDQSFFVAGWG--------GTEKETVATKLQQALITRKSL 297
            ...: .|..|||||| :...|:.|...::..|.|:|        |..|...:..||...:...|.
Worm   131 SSDL-SKLGIKPVCL-VHDDSKLLKQYKNGVVIGYGLTLGEDSSGEPKLINSQTLQSTSVPIISD 193

  Fly   298 NECRQYYN-----KGEVSDNHICATGTGIKHTCQGDSGGPVFFKHRFKNTYRVVQYGVVSFG--- 354
            ::|.:.:.     ..:::...||| |..:..|..||||||:.. |:....|  ||.|:.|:|
Worm   194 DDCVKTWRFLSLLSVKITGYQICA-GAYLHGTAPGDSGGPLLI-HKSNGEY--VQIGITSYGADG 254

  Fly   355 --GRLCGQNQPGVFASVIDMLPWI 376
              |.:.....|||:..:...:|||
Worm   255 LDGVIDQGKFPGVYTRISKYVPWI 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829
		Tryp_SPc	129..376	CDD:214473	62/266 (23%)
		Tryp_SPc	132..379	CDD:238113	64/265 (24%)
try-3	NP_001367393.1	Tryp_SPc	38..279	CDD:238113	64/267 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165900
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740