DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment grass and Corin

DIOPT Version :9

Sequence 1:	NP_651543.1	Gene:	grass / 43273	FlyBaseID:	FBgn0039494	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_058565.2	Gene:	Corin / 53419	MGIID:	1349451	Length:	1113	Species:	Mus musculus

Alignment Length:	311	Identity:	87/311 - (27%)
Similarity:	146/311 - (46%)	Gaps:	56/311 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SYLQKALCGEFNGVRHFCCPSANIQHNSKVMSLFKDENFDCGN----FLSQRVSNGYEVKLSSRP 131
            |.||:.|.     .|| .|||     .|::..|...:  |||.    .:::|:..|...:....|
Mouse   830 STLQELLV-----YRH-SCPS-----RSEISLLCSKQ--DCGRRPAARMNKRILGGRTSRPGRWP 881

  Fly   132 WMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQN-DLYEIRLGEHRISTEEDCRQQGRKK 195
            |...|:.:..|.   :||..:|:::::||.|||..|.:: |::::..|.:.:.......|....|
Mouse   882 WQCSLQSEPSGH---ICGCVLIAKKWVLTVAHCFEGREDADVWKVVFGINNLDHPSGFMQTRFVK 943

  Fly   196 KCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQKHIKPICLPITDELKEKAEQISTY 260
            ..            |:|.:|....:.:||::::|:..:....:::|:|||..:|..|.    .||
Mouse   944 TI------------LLHPRYSRAVVDYDISVVELSDDINETSYVRPVCLPSPEEYLEP----DTY 992

  Fly   261 -FVTGWGTTENGSSSDVLLQ-ANVPLQPRSACSQAY--RRAVPLSQLCVG--GGDLQDSCKGDSG 319
             ::||||  ..|:.....|| ..|.:.|...| |:|  .:.:....:|.|  .|.: |||.||||
Mouse   993 CYITGWG--HMGNKMPFKLQEGEVRIIPLEQC-QSYFDMKTITNRMICAGYESGTV-DSCMGDSG 1053

  Fly   320 GPL--QAPAQYLGEYAPKMVEFGIVSQGVVTCGQISLPGLYTNVGEYVQWI 368
            |||  :.|.   |::    ..||:.|.|.|...::..||:|:||..:|.||
Mouse  1054 GPLVCERPG---GQW----TLFGLTSWGSVCFSKVLGPGVYSNVSYFVGWI 1097

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grass	NP_651543.1	CLIP	32..90	CDD:197829	6/18 (33%)
grass	NP_651543.1	Tryp_SPc	121..371	CDD:238113	72/257 (28%)
Corin	NP_058565.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..202
		CRD_corin_1	202..331	CDD:143554
		LDLa	337..372	CDD:238060
		LDLa	374..408	CDD:238060
		Ldl_recept_a	415..445	CDD:278486
		LDLa	455..482	CDD:238060
		CRD_corin_2	522..643	CDD:143579
		Ldl_recept_a	648..682	CDD:278486
		LDLa	<695..720	CDD:238060
		LDLa	723..757	CDD:238060
		SR	758..853	CDD:214555	11/33 (33%)
		Tryp_SPc	868..1097	CDD:214473	71/258 (28%)
		Tryp_SPc	869..1100	CDD:238113	72/259 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910