Protein Alignment CG5880 and ZDHHC18

DIOPT Version :10

• Sequence 1: NP_651539.3
• Gene: CG5880 / 43268
• FlyBaseID: FBgn0039489
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_115659.1
• Gene: ZDHHC18 / 84243
• HGNCID: 20712
• Length: 388
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 70/305 - (22%)
• Similarity: 111/305 - (36%)
• Gaps: 102/305 - (33%)

  Fly    57 NYTHCLGPFFVV---GVAALTTSVVSIAYWIGLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYVMA 118
            |..:|.|...:.   ||.|||  ::.|....||.|.:....|.....|.:.  ::..::|.:||:
Human    77 NRFYCGGRLMLAGHGGVFALT--LLLILTTTGLFFVFDCPYLARKLTLAIP--IIAAILFFFVMS 137

  Fly   119 VITPAGHPPEGV----SLVEAVSM--------------------------------CGKCIAPKP 147
            .:........|:    ::.||.::                                |..|...:|
Human   138 CLLQTSFTDPGILPRATVCEAAALEKQIDNTGSSTYRPPPRTREVLINGQMVKLKYCFTCKMFRP 202

  Fly   148 PRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLY---------------MTYTTLG----- 192
            |||.|||:|:.|:.:.||||||:.||||..|:|:|:.:               :|:.||.
Human   203 PRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLRAQGSN 267

  Fly   193 -----------------CLFLI--LFGLEIGHKYLWLDHGENWTEIEPLEGQ-PVKFNLSGHIIP 237
                             |.|.|  :.||...|.||   ...|.|..|.::|. ..|......:.|
Human   268 FLSTLKETPASVLELVICFFSIWSILGLSGFHTYL---VASNLTTNEDIKGSWSSKRGGEASVNP 329

  Fly   238 VTHPNEYDEFV------LPPAVHN----------LPTPIVDTDAA 266
            .:|.:......      |||::.:          ||:||...:.|
Human   330 YSHKSIITNCCAVLCGPLPPSLIDRRGFVQSDTVLPSPIRSDEPA 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	DHHC	139..>201	CDD:396215	30/100 (30%)
ZDHHC18	NP_115659.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..67
		DHHC	191..314	CDD:396215	38/125 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..388		5/11 (45%)