Protein Alignment CG5880 and ZDHHC20

DIOPT Version :10

• Sequence 1: NP_651539.3
• Gene: CG5880 / 43268
• FlyBaseID: FBgn0039489
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001316988.1
• Gene: ZDHHC20 / 253832
• HGNCID: 20749
• Length: 365
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 90/371 - (24%)
• Similarity: 138/371 - (37%)
• Gaps: 126/371 - (33%)

  Fly    22 WSYMKHCWHSLTFNAHMNSSYASDVCLTPIFWFVDN-----YTHCLGPFFVVGVAALTTSVVSIA 81
            |||.               :|..::|:..||...:|     |......|||:.|         .:
Human    28 WSYY---------------AYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFV---------WS 68

  Fly    82 YWIGL---------PFWWAKSQLVTYFLLIVGNWLLLNVVF--HYVMAVITPAGH--PPEGVSLV 133
            ||:.:         .|:.:.|:...|           ...|  .....::..|..  |....|..
Human    69 YWMTIFTSPASPSKEFYLSNSEKERY-----------EKEFSQERQQEILRRAARALPIYTTSAS 122

  Fly   134 EAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLIL 198
            :.:..|.||...||.|.||||.|:.|||||||||||:|||||:.|:::|.|::.|:.|.|||:..
Human   123 KTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAA 187

  Fly   199 FGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDT 263
            ..||...|:        ||                        ||                :.||
Human   188 TVLEYFIKF--------WT------------------------NE----------------LTDT 204

  Fly   264 DAASPGRRRALWFMAFTNVAVVLALGSLSIWHAKLITRGETSVEAHINEAERKRHLQQQRIYINP 328
            .|     :..:.|:.|.:....:::.||..:|..|:.:..|::|:          .:.......|
Human   205 RA-----KFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIES----------FRAPTFSYGP 254

  Fly   329 ----YNFGTKKNWKLFLGLVRGRSFWRTVLLPSWHKPEGTGLSFHT 370
                ::.|..|||:...|  ..:.:|   |||.: ...|.|.||.|
Human   255 DGNGFSLGCSKNWRQVFG--DEKKYW---LLPIF-SSLGDGCSFPT 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	DHHC	139..>201	CDD:396215	35/61 (57%)
ZDHHC20	NP_001316988.1	DHHC	16..301	CDD:418707	90/371 (24%)