Protein Alignment eater and pear1

DIOPT Version :10

• Sequence 1: NP_651533.3
• Gene: eater / 43262
• FlyBaseID: FBgn0243514
• Length: 1074
• Species: Drosophila melanogaster
• Sequence 2: XP_700533.4
• Gene: pear1 / 571812
• ZFINID: ZDB-GENE-091230-1
• Length: 1020
• Species: Danio rerio
• Alignment Length: 1057
• Identity: 261/1057 - (24%)
• Similarity: 358/1057 - (33%)
• Gaps: 369/1057 - (34%)

  Fly   119 KTTNNCIPQCASGCPNGTCIT-----PNNCSCNKGYKLN-------PTTQVCLPTCKDNCAAVNG 171
            ||...|:.....||.....::     ||.||..:.:..:       |..|:....|.:..:|
Zfish     2 KTAEICVVLFVLGCVCELSLSLDPRDPNVCSLWESFTTSVKESYAQPFDQMSEEPCSEPWSA--- 63

  Fly   172 FCAAPNRC-----------------------ECNPGFIPKPKSKSFECQPKCKNGCSNGVCRAPD 213
                 |:|                       :|.|||.   :|:: :|.|:|...|.:|.|.|||
Zfish    64 -----NKCTRHRITYKTLYRQVVKMDYRRRYQCCPGFY---ESRN-KCVPRCTKECVHGRCVAPD 119

  Fly   214 KCECNKFYEKD-----IDG-----NCVPICENGCVN-GNCTAPDV----CQCLTGYTKIGHNVCL 263
            :|:|...:..|     .||     .|..:||  |.| |.|   ||    |||..|||  |.: |.
Zfish   120 RCQCEMGWRGDDCSSSCDGQHWGPGCRRLCE--CQNGGEC---DVLTGNCQCPAGYT--GQH-CH 176

  Fly   264 AVCP-----EGCQNGVCVAPNECSCNAGYTKLEGVCTP-----VCKDGCVNGFCASPEKCSCNDG 318
            ..||     :||:       .||.|..|     |:|..     |||.|.....|  .|.|
Zfish   177 DPCPVKWFGQGCR-------QECQCGTG-----GICNQTTGECVCKQGFTGTLC--EESC----- 222

  Fly   319 YEMDSENRCSPVCSGGCKN-GFCVAPGKCSCDEGYIKGTGNSCKPICSKGCENG--FCDAPEKCS 380
               ....||:..|.  |:| |.|...|.|.|..|::       .|:|::.|..|  ..:..:.|.
Zfish   223 ---PRPKRCAARCP--CQNGGICQGNGVCLCPPGWM-------GPVCTERCPPGRFGINCSKDCL 275

  Fly   381 CNDGYEMDGENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKC 445
            |::|...|.|.                  |:|.||.||   ||..|...|..|.....|..  .|
Zfish   276 CHNGGHCDQEK------------------GQCQCDAGY---TGERCNEECPVGTYGEDCKG--VC 317

  Fly   446 SCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKPICSKG--CENGFCDAP 508
            .|.:|      .||..:..|            |.|:.|:             ||  |::..|  |
Zfish   318 DCANG------ARCYNIHGG------------CLCEPGF-------------KGPRCDHRMC--P 349

  Fly   509 E---------KCSCN-----DGYEMDGENRCSPVCSGGCKNGFCVAPEKCSCDEGYSKETGNSC- 558
            |         :|.||     ..:.:.||..|.|    |....:|    ..:|.:||   .||.|
Zfish   350 EAVFGMHCQHRCLCNPLNTLSCHPLKGECTCQP----GWAGLYC----NETCAQGY---YGNGCL 403

  Fly   559 KP-ICSNG--CEN--GFCDAP--------EKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAP--G 608
            :| :|.||  |::  |.|..|        ||. |.||:...|   |...|.  |.|....:|  |
Zfish   404 EPCLCVNGGVCDSVTGQCHCPPGFTGLHCEKL-CEDGFYGKG---CLSACK--CVNSIVCSPVDG 462

  Fly   609 KCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCIAP 673
            .|.|.||:   .|..|...||:|.....|:  ..|.|.:|..      |.|            |.
Zfish   463 ACICKEGW---RGPDCSIACSEGTWGPGCN--RTCKCTNGAS------CDP------------AD 504

  Fly   674 GKCSCDEGYSKETGNSCKPIC-----SKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKN 733
            |.|.|..|:   .|.||...|     ..||:|       :|.|              |...||::
Zfish   505 GSCKCTAGW---RGASCDEPCLIGTFGPGCQN-------QCDC--------------VHDEGCES 545

  Fly   734 GFCVAPGKCSCDEGYSKETGNSCKPICSKGCENGFCEAPEKCSCNDGYEMDGENRCSPVCSGGCK 798
                ..|:|.|..|:   ||..|...|.:|.....|.  :.|||.:          |..|..
Zfish   546 ----VTGQCLCLPGW---TGVRCTQQCPEGTWGIQCN--QTCSCLN----------SATCQA--- 588

  Fly   799 NGFCIAPGKCSCDEGYSRETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSP-VCSGG 862
                 ..|.|.|..|:   .|..|:.:||.|...      ||||          ..|.| |.:..
Zfish   589 -----HTGTCLCKPGF---WGAQCQHMCSAGLFG------EKCS----------RHCPPCVHASS 629

  Fly   863 CKNGFCVAPGKCSCDEGYSKETEISCAPFCKDGCVNGLCVS--PDFCKCDDGYIFVEESKSCQLD 925
            |.:    ..|.|.|..||:       .|.|:..|..|...|  .:.|:|.:......|...|...
Zfish   630 CHH----ITGDCQCLSGYT-------GPLCEQACPVGRYGSHCSNVCRCTNNATCHHEVGLCICP 683

  Fly   926 KELLGDYSDCDKNCRNGT----CVEGICTCSKQYKLHRNEDDNNLICLPICEPECLNGLCEFPGS 986
            ....|  |||...|:.||    |.: .|:|...:.               |:|.        .|.
Zfish   684 AGWTG--SDCSLLCQAGTFGINCAQ-TCSCPPNHS---------------CDPH--------NGD 722

  Fly   987 CVCWDGESPIDGYSCQSMDSLGSLTGHEKSERHLKWVFITIVSMAFILAIITTMLIIYIFRKRSY 1051
            |||    .|..|.:|:....|..:......||........||.:..::.::..:|::|  |:|..
Zfish   723 CVC----EPGPGEACKPEQELSVMVPVSPVERDSWGAIAGIVVLVILVVLLLAVLLLY--RRRQQ 781

  Fly  1052 HVDKNEREFGVYFSPNK 1068
              ||......|.||..:
Zfish   782 --DKQSNTPVVSFSSTR 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eater	NP_651533.3	None
pear1	XP_700533.4	EMI	28..97	CDD:462204	14/79 (18%)
		Laminin_EGF	411..451	CDD:395007	13/45 (29%)