Protein Alignment eater and Pear1

DIOPT Version :10

• Sequence 1: NP_651533.3
• Gene: eater / 43262
• FlyBaseID: FBgn0243514
• Length: 1074
• Species: Drosophila melanogaster
• Sequence 2: XP_063137697.1
• Gene: Pear1 / 295293
• RGDID: 1305653
• Length: 1068
• Species: Rattus norvegicus
• Alignment Length: 1050
• Identity: 267/1050 - (25%)
• Similarity: 360/1050 - (34%)
• Gaps: 324/1050 - (30%)

  Fly   126 PQCASGCPNGTCITPNNCSCNKGYKLNPTTQVC-LPTCKDNCAAVNGFCAA------PNRCECNP 183
            |....|...|.|:.| ...|:....|....|.| :|.|.....|:....|.      ||.|....
  Rat     3 PHPEGGWKEGRCVLP-AAGCSAVLLLGALWQACAMPLCPLLLLALGLRLAGTLNSNDPNVCTFWE 66

  Fly   184 GFIPKPKS---KSFECQPKCKNGCSN-----GVCRAPD-------------------KCECNKFY 221
            .|....|.   :.|...|  ...|..     ..|..|.                   :| |..:|
  Rat    67 SFTTTTKESHLRPFSLPP--AESCDRPWEDPHTCAQPTVVYRTVYRQVVKMDSRPRLQC-CGGYY 128

  Fly   222 EKDIDGNCVPICENGCVNGNCTAPDVCQCLTGYTKIGHNVCLAVCPEG-----CQNGVCVAPNEC 281
            |.  .|.|||:|...||:|.|.||:.|||..|:.  |.: |.:.|..|     |.. :|:..|..
  Rat   129 ES--SGACVPLCAQECVHGRCVAPNRCQCAPGWR--GDD-CSSECAPGMWGPQCDR-LCLCGNSS 187

  Fly   282 SCNAGYTKLEGVCTPVCKDGCVNGFCASPEKCSCNDGYEMDSENRCSPVCSGGCK-NGFCVAP-- 343
            ||:    ...|||  .|..|.....|..|    |.||:       ..|.|...|. .|....|
  Rat   188 SCD----PRSGVC--FCPSGLQPPDCLQP----CPDGH-------YGPACQFDCHCYGASCDPRD 235

  Fly   344 GKCSCDEGYIKGTGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVA 408
            |.|.|..|   .||.||...||:|.:..||.                 |..|..:||...|   :
  Rat   236 GACFCPPG---RTGPSCNVPCSQGTDGFFCP-----------------RTYPCQNGGVPQG---S 277

  Fly   409 PGKCSCDEGYSKETGNSCKPICSKGCENGF--CDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGF 471
            .|.|||..|:       ...|||..|..||  .:..::|.|::|                   |.
  Rat   278 QGSCSCPPGW-------MGVICSLPCPEGFHGPNCTQECRCHNG-------------------GL 316

  Fly   472 CVA-PGKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKN 535
            |.. .|:|.|..||   .|:.|:..|..|....  |..|.|.|..|      .||.|.      |
  Rat   317 CDRFTGQCHCAPGY---IGDRCREECPVGRFGQ--DCAETCDCAPG------ARCFPA------N 364

  Fly   536 GFCVAPEKCSCDEGYSKETGNSC-KPICSNG-----CENG-FCDAPEKCSCNDGYEMDGENRCSP 593
            |.|:      |:.|:   ||:.| :.:|.:|     |::. .||.....||   :.|.||..|.|
  Rat   365 GACL------CEHGF---TGDRCTERLCPDGRYGLSCQDPCTCDPEHSLSC---HPMHGECSCQP 417

  Fly   594 VCSG--------------GCK-------NGFCVA-PGKCSCDEGYSKETGNSCKPICSKGCENGF 636
            ..:|              ||:       .|.|:| .|.|.|..||   ||..|..:|
  Rat   418 GWAGLHCNESCPQDTHGAGCQEHCLCLHGGVCLADSGLCRCAPGY---TGPHCANLC-------- 471

  Fly   637 CDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCIAP--GKCSCDEGYSKETGNSCKPICSKGCE 699
              .|.....|          ||..||  |:|....:|  |.|.|.||:.:  || |...|..|..
  Rat   472 --PPNTYGIN----------CSSHCS--CENAIACSPVDGTCICKEGWQR--GN-CSVPCPPGTW 519

  Fly   700 NGFCDAPEKCSCNDGYEMDSENRCSP-----VCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKPI 759
             ||       |||...:...|..|||     .|:.|.:...|..|    |.:|   :.|..|..:
  Rat   520 -GF-------SCNASCQCAHEGVCSPQTGACTCTPGWRGVHCQLP----CPKG---QFGEGCASV 569

  Fly   760 C----SKGCE--NGFCEAP-----EKC--SCNDGYEMDGENRCSPVCSGGCKNGFCIAP--GKCS 809
            |    |.||:  :|.|...     .:|  .|.:|:.  |.| ||..|:  ||||....|  |.|.
  Rat   570 CDCDHSDGCDPVHGHCRCQAGWMGTRCHLPCPEGFW--GAN-CSNACT--CKNGGTCVPENGNCV 629

  Fly   810 CDEGYSRETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKC 874
            |..|:   .|.||:..|..|.....| .|  |.||      :.:.|.|            :.|.|
  Rat   630 CAPGF---RGPSCQRPCPPGRYGKRC-VP--CKCN------NHSSCHP------------SDGTC 670

  Fly   875 SCDEGYSKETEISCAPFCKDGCVNG----LCVSPDFCKCDDGYIFVEESKSCQLDKELLGDYSDC 935
            ||..|::       .|.|.:.|..|    .|..|  |:|..|.....:..||.......|  .:|
  Rat   671 SCLAGWT-------GPDCSESCPPGHWGLKCSQP--CQCHHGATCHPQDGSCVCIPGRTG--PNC 724

  Fly   936 DKNCRN---GTCVEGICTCSKQYKLHRNEDDNNLICLPICEPECLNGLCEFPGSCVCWDGESPID 997
            .:.|.:   |.....:|.|          |...:     |.||        .|:|||..|.|
  Rat   725 SEGCPSRMFGVNCSQLCQC----------DPGEM-----CHPE--------TGACVCPPGHS--- 763

  Fly   998 GYSCQ--SMDSLGSLTGHEKSERHLKWVFITIVSMAFILAIITTMLIIYIFRKRSYHVDKNEREF 1060
            |..|:  |.:|...:.........|.    .::.:|.:..::..::.::| ..|.:...|.....
  Rat   764 GAHCKVGSQESFTIMPTSPVIHNSLG----AVIGIAVLGTLVVALVALFI-GYRHWQKGKEHEHL 823

  Fly  1061 GVYFSPNKVD 1070
            .|.:|..::|
  Rat   824 AVAYSTGRLD 833