Protein Alignment eater and CCBE1

DIOPT Version :10

• Sequence 1: NP_651533.3
• Gene: eater / 43262
• FlyBaseID: FBgn0243514
• Length: 1074
• Species: Drosophila melanogaster
• Sequence 2: XP_016881046.1
• Gene: CCBE1 / 147372
• HGNCID: 29426
• Length: 435
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 75/353 - (21%)
• Similarity: 111/353 - (31%)
• Gaps: 127/353 - (35%)

  Fly    19 QICTVNVTRNIK-------GTAVNVQTRDCCKGYKKVRSSALRCL---------AQCKVNCGSGF 67
            :||:.:.....|       |.......:.||||||.|..   :|:         |.|:..|...|
Human    45 EICSESKIATTKYPCLKSSGELTTCYRKKCCKGYKFVLG---QCIPEDYDVCAEAPCEQQCTDNF 106

  Fly    68 CTKPNVCTCKKGYVNLNNDPSNRCVPYCKGCSRGTCQSPGRCICSARHLLDKTTNNCIPQCASGC 132
            ...  :|||..||.........|..|||                     ||      |.:|||.
Human   107 GRV--LCTCYPGYRYDRERHRKREKPYC---------------------LD------IDECASS- 141

  Fly   133 PNGTCITPNNCSCNKGYKLNPTTQVCLPTCKDNCAAVNGFCAAPNRCECNPGFIPKPKSKSFEC- 196
             |||.     |:           .:|:.|            ....||||..|:|.:...|:  |
Human   142 -NGTL-----CA-----------HICINT------------LGSYRCECREGYIREDDGKT--CT 175

  Fly   197 ----------QPKCKNGCSNGVCRAPDKCECNKFYEKDIDGNCVPICENGCVNGNCTAPDVCQCL 251
                      ..|.:|....|.|.|    .|.:||:  :....:.:.:...:..| .|.|:.:.:
Human   176 RGDKYPNDTGHEKSENMVKAGTCCA----TCKEFYQ--MKQTVLQLKQKIALLPN-NAADLGKYI 233

  Fly   252 TGYTKIGHNVCLAVCPEGCQNGVCVAPNECSCNAGYTKLEGVCTPVCKDGCVNGFCASPEKCSC- 315
            ||...:..|..|. .|.|...|. ..|.|  |..|:.::            :....:.|:...|
Human   234 TGDKVLASNTYLP-GPPGLPGGQ-GPPGE--CGRGHRRV------------ITNRKSLPKAHICW 282

  Fly   316 ------------NDGYEMDSENRCSPVC 331
                        |..::...|.:.||||
Human   283 GLDNVLQLPSRRNKAHQDQREAQASPVC 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eater	NP_651533.3	None
CCBE1	XP_016881046.1	EGF_CA	134..175	CDD:214542	18/78 (23%)