Protein Alignment eater and Dkk1

DIOPT Version :10

• Sequence 1: NP_651533.3
• Gene: eater / 43262
• FlyBaseID: FBgn0243514
• Length: 1074
• Species: Drosophila melanogaster
• Sequence 2: NP_034181.2
• Gene: Dkk1 / 13380
• MGIID: 1329040
• Length: 272
• Species: Mus musculus
• Alignment Length: 255
• Identity: 59/255 - (23%)
• Similarity: 89/255 - (34%)
• Gaps: 95/255 - (37%)

  Fly   101 GTCQSPGRCICSARHLL------DKTTNNCIP-QCASGCPNGT---CITPNNCSCNKGYKLNPTT 155
            |....||..:..|..:|      .:|.:|..| .||.....|:   |.:|:..:...|     ..
Mouse    52 GAGGQPGSAVSVAPGVLYEGGNKYQTLDNYQPYPCAEDEECGSDEYCSSPSRGAAGVG-----GV 111

  Fly   156 QVCLPTCKDNCAAVNGFCAAPNRC----ECNPGFIPKPKSKSFECQPKCKNGCSNGVCRAPDKCE 216
            |:|| .|:..          ..||    .|.||                 |.|.||:|...|.
Mouse   112 QICL-ACRKR----------RKRCMRHAMCCPG-----------------NYCKNGICMPSDH-- 146

  Fly   217 CNKFYEKDIDGNCVPICENGCVNGNCTAPDVCQCLTGY-------TKIGHNVCLAVCPEGCQNGV 274
             :.|...:|:.:   |.||...:.|..|.|      ||       :||.|.       :|.:..|
Mouse   147 -SHFPRGEIEES---IIENLGNDHNAAAGD------GYPRRTTLTSKIYHT-------KGQEGSV 194

  Fly   275 CVAPNECS---CNAG--YTKLEGVCTPVCKDGCVNGFCASP-----------EKCSCNDG 318
            |:..::|:   |.|.  ::|   :|.||.|:|.|   |...           ::|.|.:|
Mouse   195 CLRSSDCAAGLCCARHFWSK---ICKPVLKEGQV---CTKHKRKGSHGLEIFQRCYCGEG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eater	NP_651533.3	None
Dkk1	NP_034181.2	Dkk1_N_Cys1	16..142	CDD:438010	27/122 (22%)
		DKK-type Cys-1	86..141		19/87 (22%)
		Dkk1_Cys2	188..270	CDD:437998	17/67 (25%)
		DKK-type Cys-2	195..269		15/60 (25%)