DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment: CG31075 and Aldh8a1

Sequence 1:NP_001247324.1 Gene:CG31075 FlyBaseID:FBgn0051075 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_848828.1 Gene:Aldh8a1 MGIID:2653900 Length:487 Species:Mus musculus

Alignment Length:477 Identity:177/478 (37%)
Similarity:268/478 (56%) Gaps:22/478 (5%)


  Fly    40 NEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNK 104
            |.::||        ::|:|.:...:|....|.:|:.||:||::||   ..|...||.:|:.::|:
Mouse    22 NSYIDS--------YDPSTGEVYCKVPNSGKEEIEAAVEAAREAF---PAWSSRSPQERSLVLNR 75

  Fly   105 LCALMDRDKAFLASLETQDNGKPYAEA-LFDVTYSILTLQYYAGWTDKFFGDTIPAG--GFVSMT 166
            |..::::....||..|::|.||....| ..|:..|:|..:::|........:.....  |.:..|
Mouse    76 LADVLEQSLEELAQAESKDQGKTLTLARTMDIPRSVLNFRFFASSNLHHVSECTQMSHLGCMHYT 140

  Fly   167 RKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVIN 231
            .:.|||:.|.|.|||.||.:|.||..||:|.|.|:|.||:|.|.:||.....|..:||.|.||||
Mouse   141 VRTPVGIAGLISPWNLPLYLLTWKIAPAIAAGNTVIAKPSEMTSVTAWMFCKLLDKAGVPPGVIN 205

  Fly   232 VVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADID 296
            :|.|.||..|.|:.:||::..::||||......:.|.:| .:.|::|||||||:|.::|:||:::
Mouse   206 IVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSA-PHCKKLSLELGGKNPAIIFEDANLE 269

  Fly   297 FAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDM 361
            ..:..|..:.|:|.|:.|...||.:|...||.||:.:.....:..|||.|.:.:...|..|....
Mouse   270 ECIPATVRSSFANQGEICLCTSRIFVQRSIYSEFLKRFVEATRKWKVGVPSDPSANMGALISKAH 334

  Fly   362 LTKVLGYIESGKKEGAKLQAG------GKRIGN-VGFFVEPTVFSDVKDDMRIAQEEIFGPVQSI 419
            |.||..|:...:.|||::..|      ...:.| .|:|:.|||.:|:||:.|...|||||||..:
Mouse   335 LEKVRSYVLKAQTEGARILCGEGVDQLSLPLRNQAGYFMLPTVITDIKDESRCMTEEIFGPVTCV 399

  Fly   420 FKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSG 484
            ..|.|.||:|.|||:|:|||||.|.:.|:.:..:.|..:.:|.||.||:.....:.||||.|.||
Mouse   400 VPFDSEEEVITRANSVRYGLAATVWSKDVGRIHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSG 464

  Fly   485 IGRELGKDGLDNYLETKTITMK 506
            ||||..||..|.:.|.||||:|
Mouse   465 IGREGAKDSYDFFTEIKTITIK 486

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG31075NP_001247324.1 ALDH-SF 33..506 CDD:299846 176/476 (37%)
Aldh8a1NP_848828.1 ALDH_F8_HMSADH 27..485 CDD:143412 174/470 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.