DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Tl and Il1rapl2

Sequence 1:NP_001262995.1 Gene:Tl FlyBaseID:FBgn0262473 Length:1117 Species:Drosophila melanogaster
Sequence 2:NP_109613.1 Gene:Il1rapl2 MGIID:1913106 Length:686 Species:Mus musculus

Alignment Length:334 Identity:76/335 (23%)
Similarity:147/335 (44%) Gaps:55/335 (16%)


  Fly   819 LAGFTAALYYKFQTEIKIW-LYAHNLLLW----FVTEEDLDKDKKFDAFISYSHKDQSFI----- 873
            |||...|::......:.:: .|...|:|:    |..:|..|.:|::||::||:..||..:     
Mouse   357 LAGGLGAIFLLLILLLVVYKCYNIELMLFYRQRFGGDETTDDNKEYDAYLSYTKVDQDTLDCDNT 421

  Fly   874 --EDY---LVPQLEHGPQKFQLCVHERDWLVGGHIPENIMRSVADSRRTIIVLSQNFI-KSEWAR 932
              |.:   ::|.:......::|.:.|||.:..|...|::.|.|..|||.||||:.::| :..|:.
Mouse   422 EEEQFALEILPDVLEKHYGYKLFIPERDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSI 486

  Fly   933 LEFRAAHRSALNEGRSRIIVIIYSDI-GDVEKLD-EELKAYLKMNTYLKWGDP-------WFWDK 988
            .|..:...:.|..|..::|:|..::: |.|...: |.||..:|:.:.:||..|       .||..
Mouse   487 FELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKHNIKLLSLIKWKGPKSSKLNSKFWKH 551

  Fly   989 LRFALPHRRPVGNIGNGALIKTALKGSTDDKLELIKPSPVTPPLTTPPAEATKNPLVAQLNGVTP 1053
            |.:.:|.::. ..:.:..::.:|.:|...:    ::|   .|.:......||..|..|.|.....
Mouse   552 LVYEMPIKKK-EMLSHCHVLDSAEQGLFGE----LQP---IPSIAMTSTSATMVPSQADLPEFHH 608

  Fly  1054 HQAIMIANGKNGLTNLYTPNG---KSHGNGH---------INGAFIINTNAKQSDVXDWEKAELF 1106
            ..::.:.:...|..:....|.   .|.||.|         :||...:|.:.|:::          
Mouse   609 SDSMQMRHCCRGYQHEMPANTLSVPSLGNHHTYCNLPLTLLNGQLPLNNSLKETE---------- 663

  Fly  1107 QFDPDDELL 1115
            :|..::.||
Mouse   664 EFSRNNPLL 672

Known Domains:


GeneSequenceDomainRegion External IDIdentity
TlNP_001262995.1 LRR_8 174..233 CDD:290566
leucine-rich repeat 176..198 CDD:275380
leucine-rich repeat 199..222 CDD:275380
LRR_RI 216..542 CDD:238064
LRR_8 221..281 CDD:290566
leucine-rich repeat 223..270 CDD:275380
leucine-rich repeat 271..294 CDD:275380
leucine-rich repeat 295..320 CDD:275380
leucine-rich repeat 321..343 CDD:275380
LRR_8 342..402 CDD:290566
leucine-rich repeat 344..367 CDD:275380
leucine-rich repeat 368..391 CDD:275380
LRR_8 390..450 CDD:290566
leucine-rich repeat 392..415 CDD:275380
leucine-rich repeat 416..439 CDD:275380
leucine-rich repeat 440..474 CDD:275380
leucine-rich repeat 475..498 CDD:275380
LRR_8 477..534 CDD:290566
leucine-rich repeat 499..520 CDD:275380
leucine-rich repeat 523..552 CDD:275380
LRRCT 561..619 CDD:214507
LRRNT 631..667 CDD:214470
leucine-rich repeat 664..693 CDD:275380
LRR_8 669..726 CDD:290566
leucine-rich repeat 694..715 CDD:275380
leucine-rich repeat 716..737 CDD:275380
LRRCT 751..800 CDD:214507
TIR 858..996 CDD:214587 43/158 (27%)
Il1rapl2NP_109613.1 Ig1_IL1RAPL-1_like 32..133 CDD:143304
Ig2_IL1R_like 146..237 CDD:319309
IG_like 250..347 CDD:214653
TIR 401..559 CDD:214587 43/158 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 0 Normalized mean entropy S8062
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.950

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