Protein Alignment Tl and CG18480

DIOPT Version :10

• Sequence 1: NP_001262995.1
• Gene: Tl / 43222
• FlyBaseID: FBgn0262473
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_609761.1
• Gene: CG18480 / 34920
• FlyBaseID: FBgn0028518
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 214
• Identity: 62/214 - (28%)
• Similarity: 91/214 - (42%)
• Gaps: 45/214 - (21%)

  Fly   355 KTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTL 419
            |.|.:..:|....:..||||.|.:|.:.|..|..|.:|.:|.|..|.:..:.||.|..|..|..|
  Fly    63 KRLISANIEIPTTVELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYL 127

  Fly   420 VMSRNRLRTIDSRAFVSTNGLRHLHLDHNDIDL--QQPLLDIMLQTQINSPFGYMHGLLTLNLRN 482
            .:|.|||..||.....|.|.|.||:|:.|.:..  :.|:|        .||     .|.:|||||
  Fly   128 DLSYNRLEQIDEHILESNNQLIHLNLEGNKLSTLGKGPIL--------RSP-----SLRSLNLRN 179

  Fly   483 NSIIFVYNDWKNTMLQLRELDLSYNNISSLGYEDLAFLSQNRLHVNMTHNKIRRIALPEDVHLGE 547
            :.:..:.....:.:.|||:|||:.|.:.:|.                          |.|.|.
  Fly   180 SQVNQLGTQLLSALPQLRQLDLAQNLLLTLS--------------------------PGDFHA-- 216

  Fly   548 GYNNNLVHVDLNDNPLVCD 566
              ..||..:::.:||..||
  Fly   217 --PRNLASLNVEENPFNCD 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tl	NP_001262995.1	LRR_8	174..233	CDD:404697
		leucine-rich repeat	176..198	CDD:275380
		leucine-rich repeat	199..222	CDD:275380
		LRR	222..576	CDD:443914	62/214 (29%)
		leucine-rich repeat	223..270	CDD:275380
		leucine-rich repeat	271..294	CDD:275380
		leucine-rich repeat	295..320	CDD:275380
		leucine-rich repeat	321..343	CDD:275380
		leucine-rich repeat	344..367	CDD:275380	3/11 (27%)
		leucine-rich repeat	368..391	CDD:275380	9/22 (41%)
		leucine-rich repeat	392..415	CDD:275380	8/22 (36%)
		leucine-rich repeat	416..439	CDD:275380	9/22 (41%)
		leucine-rich repeat	440..474	CDD:275380	9/35 (26%)
		leucine-rich repeat	475..498	CDD:275380	6/22 (27%)
		leucine-rich repeat	499..520	CDD:275380	7/20 (35%)
		leucine-rich repeat	523..552	CDD:275380	3/28 (11%)
		LRRCT	561..619	CDD:214507	4/6 (67%)
		LRRNT	631..667	CDD:214470
		PPP1R42	<660..752	CDD:455733
		leucine-rich repeat	664..693	CDD:275380
		leucine-rich repeat	694..715	CDD:275380
		leucine-rich repeat	716..737	CDD:275380
		LRRCT	751..800	CDD:214507
		TIR	858..996	CDD:214587
CG18480	NP_609761.1	LRR	<66..>230	CDD:443914	57/206 (28%)
		leucine-rich repeat	76..99	CDD:275380	9/22 (41%)
		leucine-rich repeat	100..123	CDD:275380	8/22 (36%)
		leucine-rich repeat	124..147	CDD:275380	9/22 (41%)
		leucine-rich repeat	148..171	CDD:275380	9/35 (26%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	10/52 (19%)