Protein Alignment tx and TCF3

DIOPT Version :10

• Sequence 1: NP_524516.2
• Gene: tx / 43190
• FlyBaseID: FBgn0288888
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: XP_047295214.1
• Gene: TCF3 / 6929
• HGNCID: 11633
• Length: 683
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 58/212 - (27%)
• Similarity: 84/212 - (39%)
• Gaps: 58/212 - (27%)

  Fly     1 MKSNTYELHNYA-------DLNDMARATDSKDSRKRKTASARGEKYSLRQKRQKRGSNEDGESAN 58
            :..:|..:||:|       .|.|::|..||.....|..|:|...:.       ||...||.|:.:
Human   481 LAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEI-------KREEKEDEENTS 538

  Fly    59 LADFQLELDPIAEPASKSRKNAPTKSKTK--------APP-----LSKYRRKTANARERTRMREI 110
            .||...|        .|....|| :::|.        .||     ..|.||...|||||.|:|:|
Human   539 AADHSEE--------EKKELKAP-RARTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDI 594

  Fly   111 NTAFETL-RHCVPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIRDPSYESEFIGECLEES 174
            |.||:.| |.|       :...|:.:..||:..|..|:..|..|...:|             |.:
Human   595 NEAFKELGRMC-------QLHLNSEKPQTKLLILHQAVSVILNLEQQVR-------------ERN 639

  Fly   175 ANREARVDLEANEEAEV 191
            .|.:|.. |:..||.:|
Human   640 LNPKAAC-LKRREEEKV 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tx	NP_524516.2	bHLH_TS_taxi_Dei	95..157	CDD:381437	23/62 (37%)
TCF3	XP_047295214.1	SF-CC1	503..>603	CDD:273721	36/115 (31%)
		bHLH_E-protein_TCF4_E2-2	572..656	CDD:381515	32/105 (30%)