Protein Alignment tx and NEUROD4

DIOPT Version :10

• Sequence 1: NP_524516.2
• Gene: tx / 43190
• FlyBaseID: FBgn0288888
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_067014.2
• Gene: NEUROD4 / 58158
• HGNCID: 13802
• Length: 331
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 73/281 - (25%)
• Similarity: 104/281 - (37%)
• Gaps: 66/281 - (23%)

  Fly    43 QKRQKRGSNEDGESANLADFQLELDPI------AEPASKSRKNAPTKSKTKAPPLSKY--RRKTA 99
            |...|...:..|....|:....|.|.|      .|...|.::..|.|.|.....|.::  ||..|
Human    28 QNEVKEEESRPGTYGMLSSLTEEHDSIEEEEEEEEDGEKPKRRGPKKKKMTKARLERFRARRVKA 92

  Fly   100 NARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYI-------------- 150
            ||||||||..:|.|.:.||..:|       ..:..:||:||.|||||..||
Human    93 NARERTRMHGLNDALDNLRRVMP-------CYSKTQKLSKIETLRLARNYIWALSEVLETGQTPE 150

  Fly   151 -----TMLTDSIRDPSYESEFIGECLE---ESANREARVDLEANEEAEVE----------LPVP- 196
                 .||...:..|:  |..:..||:   :|...|...|.....::.:.          ||.|
Human   151 GKGFVEMLCKGLSQPT--SNLVAGCLQLGPQSVLLEKHEDKSPICDSAISVHNFNYQSPGLPSPP 213

  Fly   197 --------VAKKPAKTKGSGKKSSAASKRQSQKQAKIVPQIPPIS-SGESCYATSSIGSP-ASSA 251
                    :..||...|..|:.|..:............|..||:| ||.  ::....||| ...:
Human   214 YGHMETHLLHLKPQVFKSLGESSFGSHLPDCSTPPYEGPLTPPLSISGN--FSLKQDGSPDLEKS 276

  Fly   252 YASL----SSSSNSHSSSSSP 268
            |:.:    |||.:|....|:|
Human   277 YSFMPHYPSSSLSSGHVHSTP 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tx	NP_524516.2	bHLH_TS_taxi_Dei	95..157	CDD:381437	29/80 (36%)
NEUROD4	NP_067014.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..80		12/51 (24%)
		bHLH_TS_NeuroD4_ATOH3	59..145	CDD:381564	33/92 (36%)
		Neuro_bHLH	146..264	CDD:463621	23/121 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..265		6/20 (30%)