Protein Alignment tx and OLIG2

DIOPT Version :10

• Sequence 1: NP_524516.2
• Gene: tx / 43190
• FlyBaseID: FBgn0288888
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_005797.1
• Gene: OLIG2 / 10215
• HGNCID: 9398
• Length: 323
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 69/259 - (26%)
• Similarity: 104/259 - (40%)
• Gaps: 84/259 - (32%)

  Fly    73 ASKSRKNAPTKSKTKAPPLSKYRRKTANARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKL 137
            ||.::|:   |.:...|.|.:.|.| .|:|||.||.::|.|.:.||..:|.| .|...    .||
Human    91 ASSTKKD---KKQMTEPELQQLRLK-INSRERKRMHDLNIAMDGLREVMPYA-HGPSV----RKL 146

  Fly   138 TKITTLRLAMKYITMLTDSIRD-PSYESEFIG---------EC--LEESANREARVDLEANEEAE 190
            :||.||.||..||.|||:|:.: ....||..|         .|  |..||
Human   147 SKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSA--------------- 196

  Fly   191 VELPVPVAKKPAKTKGSGKKSSAASKRQSQKQAKIVPQIPPISSGESCYATSSIGSPASSAYASL 255
               |:|.|          ....||:...:...|...|.:||                 ::|.|:.
Human   197 ---PLPAA----------TAHPAAAAHAAHHPAVHHPILPP-----------------AAAAAAA 231

  Fly   256 SSSSNSHSSSSSPGLELDSLVGLNGISALDSL-----LLDTSDGDSLSCLSPGYGSLLTGSGES 314
            ::::.:.||:|.||         :|:.::.|:     ||.:....:.:.|..|.|    |||.|
Human   232 AAAAAAVSSASLPG---------SGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGG----GSGAS 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tx	NP_524516.2	bHLH_TS_taxi_Dei	95..157	CDD:381437	28/61 (46%)
OLIG2	NP_005797.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107		5/18 (28%)
		bHLH_TS_OLIG2	95..179	CDD:381510	35/92 (38%)