Protein Alignment osy and Abca14

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_017167760.1
• Gene: Abca14 / 67928
• MGIID: 2388708
• Length: 1719
• Species: Mus musculus
• Alignment Length: 846
• Identity: 173/846 - (20%)
• Similarity: 331/846 - (39%)
• Gaps: 194/846 - (22%)

  Fly    50 VRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGR 114
            ::..:|.:....:..:.::.|::.:.:|.|..|||.:|.||||.||.:.|......|::::.|..
Mouse   558 IQHLYKEFILKNSTLMAVNDLSLNLYEGQITVLLGHNGAGKTTTLSILTGLYLPTRGKVYISGYD 622

  Fly   115 PGS-----RGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNLP 174
            ..|     |.|      :|..||:..|:...|:.|.|.::.:|..:...:....|..:|....|.
Mouse   623 ISSDMVQIRKS------LGLCPQDDLLFPMLTVSEHLHFYCVIKGIPLQNQSRETNRMLTSFGLL 681

  Fly   175 NASKFV-KNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVII 238
            ..|..: |:||||.:|::|:.:||:.:.:::||||||.|:|||.|::.||.|....|:  .|:::
Mouse   682 QQSNTMSKDLSGGMKRKLSIIIALIGDTKVVILDEPTSGMDPVSRRATWDLLQHYKKD--RTILL 744

  Fly   239 TTHYIDEC-AQAHMIGLLRGGKMLAEESPDYLRQQYNA----------DSLEDVFLKLSVLQNMG 292
            |||::||. .....|.:|..|.:....|..:|::.|..          ||.::...:|.......
Mouse   745 TTHHMDEADVLGDRIAILVMGILKCCGSSLFLKKLYGVGYHLVIVKTPDSNDEKIFQLIKNYIPT 809

  Fly   293 KRRRSSIAQE---IVEQVTVPAISNPALDMSDEQHAAEISGEFG------DNISMSSAARDPIST 348
            .:..:::|.|   |:.:......:....|:.::|....||| ||      |.:....:..:.:..
Mouse   810 AKMETNVAAELSFILPKEHTHRFAELFTDLEEKQEELGISG-FGVSMTTMDEVFFKVSNLEDLKL 873

  Fly   349 TAPAAPP----------------LPPPQEIP--------TSF---WYNLHVMQSHHLHALIWKNF 386
            ....||.                :|...|.|        :||   | :|::.|   ..|:..|..
Mouse   874 NTEIAPSASIVSQSSNEDNQNMNVPRNFERPGYSRRHLDSSFNAGW-SLYIQQ---FRAMFIKRV 934

  Fly   387 LWMMRNVGVMLF----IVGLPVVQILLFCYAIGHDPTGLKLAVANHEMSGEMIMEQFCPVHTGCN 447
            ::..|...::|.    ::||..:.|....:::..:|.    .|.:.|..||.|:.  ..|....|
Mouse   935 MFSWRYWKLLLLQLLALLGLMYLLIKGISFSVPKEPA----RVMDLEQYGETIVP--FSVSGDPN 993

  Fly   448 QTMLSCRYLDMLVKNKSMVVQYVTDDEMAYEEVRKGRAWAALVIQPNYTASLMERVEDGRYAEDG 512
            .|.:..:.|:.::|.|...:..|..|...|....|...::.:|                .::.|.
Mouse   994 LTQILTKNLETMLKAKKQKIHEVQGDMKNYLLTSKDCIYSCIV----------------AFSLDV 1042

  Fly   513 TIESSDLAVRMDWSNQQ-----------ISQLLYR-----DLQYTFFNFVGDMLSDCDVNPKLGR 561
            |.|....   :.|.|.:           :..::|:     |...|..|           ||:..|
Mouse  1043 TTEEKTF---IFWFNNEAYHAAPLSLSILDNIIYKYLSGPDATITVSN-----------NPQPQR 1093

  Fly   562 VPVDFQHPVYGYRNPNFTDFAAPGVILTIIFFLAVAVTSGAMLIDRNEGMLER---CLVAGI--- 620
            |..|         ..|....:...::..::|.::: .|||..|:...|.:.:.   ..|:|:
Mouse  1094 VTKD---------KSNERSISGIQIVFNLLFGMSI-FTSGFCLMTVTERVSKAKHIQFVSGVYTL 1148

  Fly   621 ---------------------------TGPEILLSQ---VVTQFTVML---SQTTFVLIVSFYFF 652
                                       |..:|||.:   :.|.|.:||   |...|:.::||::.
Mouse  1149 NFWLSALLWDLIIHFVACVLLLVVFLYTDVDILLEKYHFLDTMFILMLFGWSIIPFIYLLSFWYN 1213

  Fly   653 ELTLVGNIWLVVAL---CILNGLCGMSFGFVISCAVDTERTATYVAMGS--FLPIVMLCGIIWPI 712
            ..|   |.::.:.:   |:  |...:....|:....|.:.:...:.:.|  .|||......|:..
Mouse  1214 NST---NAYIKIFVFNHCL--GFISIIVDAVVQIIPDIKTSTKNLILNSMLLLPIYNFGMSIYKY 1273

  Fly   713 EGMFPLLQFFTAFLPLTKPTESMRSILQRGWGIDNPV-------VYNGFISISSWVLVFLVLTIL 770
            ..:..:.:..:: |.......|.:|.:     ||.|:       :.....::::..|::.:|.||
Mouse  1274 YNIHEIRKLCSS-LGYINTIPSCKSQI-----IDIPIYSMNQKAIGRHVTAMAATGLIYFILIIL 1332

  Fly   771 L 771
            |
Mouse  1333 L 1333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	70/251 (28%)
		YadH	578..773	CDD:440604	42/245 (17%)
Abca14	XP_017167760.1	rim_protein	<128..1709	CDD:130324	173/846 (20%)