Protein Alignment osy and abca3b

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_009297489.1
• Gene: abca3b / 564344
• ZFINID: ZDB-GENE-050517-2
• Length: 1703
• Species: Danio rerio
• Alignment Length: 900
• Identity: 190/900 - (21%)
• Similarity: 350/900 - (38%)
• Gaps: 234/900 - (26%)

  Fly    23 DLDLAARRRLFISQPSTLATRRQQAVCVRRAHKMYG-SSKNPNVVLDGLNMTVPKGSIYGLLGAS 86
            |.:.|::......:|:.|..    .|.::|..|::. .:|:...|.| |.:.:.:|.|..|||.:
Zfish   507 DAEKASKGEFMEEEPAGLVA----GVKIKRLAKVFKVGNKSKEAVRD-LTLNMFEGQITVLLGHN 566

  Fly    87 GCGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGI 151
            |.||||.||.:.|....:||..:: .|....:...:....:|..||...|:...|:||.|:::..
Zfish   567 GAGKTTTLSMLTGLFPPSSGRAYI-NGYDICQDMALIRRSLGLCPQHDVLFDNLTVREHLLFYTQ 630

  Fly   152 ISAMSKGDIEDRTEFLLKLLNLP---NASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGV 213
            :....:..|....:.::::|||.   ||.  .|.||||.:|::|:.:||:.:.::::|||||.|:
Zfish   631 LKGYPREKIPGEVDRIIRILNLEDKRNAK--CKTLSGGMKRKLSIGIALIGDSKVVMLDEPTSGM 693

  Fly   214 DPVLRQSIWDHLVDITKNGHTTVIITTHYIDECAQAHMIG----LLRGGKMLAEESPDYLRQQYN 274
            ||..|::.|| |:...|.|. |:::|||::||   |.::|    ::..|::....||.:|:.:|.
Zfish   694 DPSARRATWD-LLQGEKRGR-TILLTTHFMDE---ADLLGDRIAIMASGELQCCGSPLFLKNKYG 753

  Fly   275 AD----SLEDVFLKLSVLQNM------GKRRRSSIAQEI-------------------------- 303
            |.    .::|.|..:|.:..:      .....||...|:
Zfish   754 AGYHMVIVKDAFCNVSEITRLVHMYVPDATLESSAGAELSYILPKESTSRFELLFAELEMNRDEL 818

  Fly   304 -----------VEQV------------TVPAISNPALDMSDEQH--------AAEISG------- 330
                       :|:|            .:.||..|||....|:.        ::.|||
Zfish   819 GIASYGASVTTMEEVFLRVGKLVDSSLDIQAIQLPALQYQHERRSHDWTMDDSSSISGMTDVTDF 883

  Fly   331 --------EFGDNISMSSAARDPISTTAPAAPPLPPPQEIPTSFWYNLHVMQSHHLHALIWKNFL 387
                    |.|.||.:::.||                          |::.|   .:|:..|..|
Zfish   884 TDSCTMISEDGSNIKLNTGAR--------------------------LYMQQ---FYAMFLKRAL 919

  Fly   388 WMMRNVGVML--FIVGLPVVQILLFCYA----IGHDPTGLKLAVANHEMSGEMIMEQFCPVHTGC 446
            :..||..||:  |:|.| :..:|....|    ..|....|:||:..:   |:..:......:.|.
Zfish   920 YSWRNWKVMVAQFLVPL-IFTVLALVVARSLPSSHSSPQLRLALKQY---GQTHVPVAVEANAGP 980

  Fly   447 NQTMLSCRYLDMLVKNKSMVVQYVTD--DEMAYEEVRKGRAWAALVIQPNYTASLMERVEDGRYA 509
            ..::|:..|...|....::....:||  :.:.|...|:|.|:                  :....
Zfish   981 LASLLAEIYTTQLPSQNAIAAPNITDFSEYVLYNAQREGGAF------------------NEHCV 1027

  Fly   510 EDGTIESSDLAVRMDWSNQQ-----ISQLLYRDLQYTFFNFVGDMLSDCDVNPKLGR--VPVDFQ 567
            ......|||:   :.:.|.|     .:.|:..|      |.:..:|:..:.:.:.|.  :|.:..
Zfish  1028 VGAAFRSSDV---IGYFNNQGYHTPATALMLVD------NALFKLLAGPNASIQTGNDPMPRNVS 1083

  Fly   568 HPVYGYRNPNFTDFAAPGVILTIIFFLAVAVTSGAMLIDRNEGMLERCL--VAGITGPEILLSQV 630
            .......:.:.|.||   :.:.:::.:|...::.|:|:.....:..:.:  |:|:.......|.:
Zfish  1084 ETAQSQLSESQTGFA---IAINLMYGMASLASTFALLLVSERSVKSKHVQQVSGVYLTNFWFSAL 1145

  Fly   631 VTQFTVMLSQTTFVLIVSFYF---------------FELTLVGNIWLVVALCILNGLCGMSFGFV 680
            :......|.....:|:|...|               |.|.|.|  |.|:.|..|     |||.|.
Zfish  1146 LWDLINFLLPCLLMLVVFRVFSVKAFVAQNHLVDVLFLLLLYG--WAVIPLMYL-----MSFLFS 1203

  Fly   681 ISCAVDT--------ERTATYVAMGSF----LPIVMLCGIIWPIEGMFP---LLQFFTAFL---- 726
            .:....|        ..|||::|:...    |.::.|..::..:..:||   |...||.|.
Zfish  1204 TAATAYTRLTIFNIISGTATFLAVTIMTIPELNLLHLSHLLDKVFLIFPNYCLGMSFTEFYQNYE 1268

  Fly   727 --------PLTKPTESMRSIL--QRGWGIDNPVVYNGFISISSWVLVFLVLTILL 771
                    ||.|......:|.  ...:.::.|.|....:::|...:||::|..|:
Zfish  1269 MITFCTSSPLAKYICKYYNITYQMNYFSMEEPGVGRFLVALSLQGVVFIILLFLI 1323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	75/246 (30%)
		YadH	578..773	CDD:440604	49/239 (21%)
abca3b	XP_009297489.1	rim_protein	1..>95	CDD:130324
		rim_protein	<122..1695	CDD:130324	190/899 (21%)