Protein Alignment osy and abca4b

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_021322694.1
• Gene: abca4b / 555506
• ZFINID: ZDB-GENE-050517-4
• Length: 2327
• Species: Danio rerio
• Alignment Length: 982
• Identity: 198/982 - (20%)
• Similarity: 330/982 - (33%)
• Gaps: 343/982 - (34%)

  Fly    33 FISQPSTLATRRQQAVCVRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCI 97
            |..:|.:|..    .|.|:...|||.....|.|  |.|||...:..|...||.:|.||||.||.:
Zfish   969 FEPEPESLLI----GVSVQDLVKMYNRYSRPAV--DCLNMNFYESQITSFLGHNGAGKTTTLSIL 1027

  Fly    98 VGRRRLNSGEIWVLGGRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIED 162
            .|.....||..::.|....:....: ...:|..||...|:...|:.|.::::.::......:.|.
Zfish  1028 TGLFPPTSGTAYIYGRDIRTEMDAI-RQSLGMCPQHNILFKHLTVEEHILFYSLMKGREHKEAEQ 1091

  Fly   163 RTEFLLKLLNLPN-ASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLV 226
            ..|.:|:.|.||: ..:..:|||||.||::|:|:|.:....::||||||.||||..|:||||.|:
Zfish  1092 EVENMLEDLGLPHKRDEEAQNLSGGMQRKLSVAMAFVGGSRVVILDEPTSGVDPYSRRSIWDLLL 1156

  Fly   227 DITKNGHTTVIITTHYIDEC-AQAHMIGLLRGGKMLAEESPDYLRQQYNADSLEDVFLKLSVLQN 290
            .. :.|. |||::||::||. ..:..:.::..||:....||.:|:..:.      |...|::::.
Zfish  1157 KY-RTGR-TVILSTHHMDEADLLSDRVAIISKGKLHCSGSPLFLKNCFG------VGFYLTLVRR 1213

  Fly   291 MGKRRRS----SIAQEI--------------------------VEQVT------VPAISNPALDM 319
            |..:|:.    ..|.|.                          ||.:|      ||...  .::|
Zfish  1214 MKDQRKKENECDCASECSCTCSTCTRYKEESQALQPERVLDGNVESITTLIHHHVPEAK--LIEM 1276

  Fly   320 SDEQ--------------HAA---EISGEFGD------NISMSSAARDPISTTA--PAAPPLPPP 359
            ..::              :|:   |:....||      .||.:|.....:..||  .||.....|
Zfish  1277 IGQEMTYLLPNKGFKYRAYASLFRELEETLGDMGLSSFGISDTSLEEIFLKVTADGEAANSSVTP 1341

  Fly   360 QEIPTSFW-------------------------------------------YNLHVMQSHHLHAL 381
            ::     |                                           ::|.:.|   .|||
Zfish  1342 EQ-----WMLQQRKNGNGFMKDTGLAEDANGVGASLESDSSEGRASRQVKGFSLVLKQ---FHAL 1398

  Fly   382 IWKNFLWMMRNVGVMLFIVGLP---VVQILLFCYAI---GHDPT--------GLKLAVANHEMSG 432
            :.|.|....|:....|..:.||   |:..|:|...:   |..|.        |.:....::|...
Zfish  1399 LVKRFHHATRSHKDFLAQIVLPASFVLIALVFTMIVPPFGEYPCLTLTPWMYGPQFTFISNEQPS 1463

  Fly   433 EMIMEQFCPVHTGCNQTMLSCRYLDMLVKNKSMVVQYVTDD--EMAYEEVRKGRAWAALVIQPNY 495
            ...|:.|                :..|:|:..|..:.:.:.  |..:..:.....|....:.|..
Zfish  1464 HPKMKHF----------------IQTLLKDPGMGTRCMANQPLENIFTCLNSSSDWEVPPVSPEV 1512

  Fly   496 TASLMERVEDGRYAEDGTIESSDLAVRM-------------------------DWSNQQISQLL- 534
            :..|.....|.|........|:||.:.|                         |.:|:.||..|
Zfish  1513 SNILSSPEWDSRNPSPSCECSTDLKLTMLPMCPAGAGGLPPRQRKEPTGDILLDMTNRNISDYLV 1577

  Fly   535 --YRDLQYTFFN-------------FVGDMLSDCDVNP--------KLGRVP------------- 563
              |..|..|...             .||..|...||:|        :|||:.
Zfish  1578 KTYTKLIKTSLKSKYWVNEQRYGGISVGGRLPILDVDPEEIQNIFSQLGRMMNIRGGRYSKSAMD 1642

  Fly   564 -----VDFQHPVYG----YRNPNFTDFAAPGVILTIIFFLAVAVTSGAMLIDRNEGMLERCL--- 616
                 :.:....|.    |.|..:...|:         ||.||          |..:|...|
Zfish  1643 ELETFLHYMESEYNVKVWYNNKGWHAMAS---------FLNVA----------NNAILRAYLPPH 1688

  Fly   617 -------VAGITGPEILLSQVVTQFTVMLSQTTFVLIVSFYFFELTLVGNIWLVVALCILNGLCG 674
                   :..|..|..|..:.:::.||:   ||                ::..|||:|::..:..
Zfish  1689 ANPSDYGITAINHPLNLTKEQLSEVTVL---TT----------------SVDAVVAICVIFAMSF 1734

  Fly   675 MSFGFVISCAVDTERTATYVAMGSFLPIVMLCGIIWPIEGMFPLLQFFTAFL------------- 726
            :...||:....:....|.::..               :.|:.||:.:|..|.
Zfish  1735 IPASFVLYLIQERVTKAKHLQF---------------VSGVSPLVYWFANFFWDMLNYSVSTAMV 1784

  Fly   727 ----------PLTKPTE--SMRSIL-QRGWGIDNPVVY-------------------NGFISISS 759
                      ..|.||.  ::.::| ..||.: .|::|                   |.||.|:|
Zfish  1785 VAIFVGFDKKCYTSPTNLPALIALLCLYGWSV-TPMMYPLSYMFNVPSTAYVSLSCINLFIGINS 1848

  Fly   760 WVLVFLV 766
            ..:.|::
Zfish  1849 SAITFIL 1855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	76/236 (32%)
		YadH	578..773	CDD:440604	41/244 (17%)
abca4b	XP_021322694.1	rim_protein	1..2315	CDD:130324	198/982 (20%)