Protein Alignment osy and Abca17

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_001026792.2
• Gene: Abca17 / 381072
• MGIID: 3625331
• Length: 1733
• Species: Mus musculus
• Alignment Length: 803
• Identity: 186/803 - (23%)
• Similarity: 314/803 - (39%)
• Gaps: 244/803 - (30%)

  Fly    42 TRRQQAVCVRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSG 106
            |.:...:.::..:|::.|.::....:..|:|.:.||.:..|||.:|.||||:.|.:.|....:.|
Mouse   513 TNQMNTIEIQHLYKVFYSGRSKRTAIRDLSMNLYKGQVTVLLGHNGAGKTTVCSVLTGLITPSKG 577

  Fly   107 EIWVLGGRPGS-----RGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDRTEF 166
            ..::.|.....     |.|      :|:.||...|:..||:.:.|.::|.:..:|..|..::|:.
Mouse   578 HAYIHGCEISKDMVQIRKS------LGWCPQHDILFDNFTVTDHLYFYGQLKGLSPQDCHEQTQE 636

  Fly   167 LLKLLNLP----NASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVD 227
            :|.||.|.    :.|||   ||||.:|::|:.:||:...::|||||||.|:|...|::|||.|..
Mouse   637 MLHLLGLKDKWNSRSKF---LSGGMKRKLSIGIALIAGSKVLILDEPTSGLDSPSRRAIWDLLQQ 698

  Fly   228 ITKNGHTTVIITTHYIDECAQAHMIG----LLRGGKMLAEESPDYLRQQYNA------------- 275
              :.|..||::|||::||   |.::|    :|..|::....||.:|:|:|.|
Mouse   699 --QKGDRTVLLTTHFMDE---ADLLGDRIAILAKGELQCCGSPSFLKQKYGAGYYMTIIKTPLCD 758

  Fly   276 -DSLEDVF---LKLSVLQNMGKRRRSSIAQEIVEQVTVP--------AISNPALDMSDEQHAAEI 328
             ..|.:|.   :..:||:       |:|.:|::  ||:|        |:.|   |:...|....|
Mouse   759 TSKLSEVIYHHIPNAVLE-------SNIGEEMI--VTLPKKTIHRFEALFN---DLELRQTELGI 811

  Fly   329 SGEFGDNISMSSAARDPISTTAPAAPPLPPPQEIPTSFWYNLHVMQSHHLHALIWKNFLWMMRNV 393
            | .|..:::........:...|      .|...:.|...::||.:..||
Mouse   812 S-TFATSVTTMEEVFIRVCKLA------DPSTNVLTEKRHSLHPLPRHH---------------- 853

  Fly   394 GVMLFIVGLPVVQILLFCYAIGHDPTGLKLAVANHEMSGEMIMEQFCPVHTG-CNQTMLSCRYLD 457
                   .:||.:|.  |...|..|..               .||...::|| |   :|..::..
Mouse   854 -------RVPVDRIK--CLHSGTFPVS---------------TEQPMRLNTGFC---LLCQQFYA 891

  Fly   458 MLVKNKSMVVQYVTDDEMAYEEVRKGRAW----AALVIQPNYTASLMERVEDGRYAEDGTIESSD 518
            ||:|            ::.|..    |.|    :..|:.|
Mouse   892 MLLK------------KITYSR----RNWMLVLSVQVLLP------------------------- 915

  Fly   519 LAVRMDWSNQQISQLLYRDLQYTFFNFVGDMLSDCDVNPKLGRVPVDFQHPVYG----------- 572
            ||:.|              |..|||||         ...||..||::.....||
Mouse   916 LAIIM--------------LSLTFFNF---------KLRKLDNVPLELTLQTYGQTIVPFFIAEN 957

  Fly   573 -YRNPNFTDFAAPGVILTIIFFLAVAVTSGAMLIDRNEGMLERCLV-AGITGPEIL--LSQVVTQ 633
             :.:|..:|           .|:.:.|.:|.:.: |.:|.:|..|: .....||..  |..|...
Mouse   958 SHLDPQLSD-----------DFVKMLVAAGQVPL-RIQGSVEDFLLKKAKEAPEGFDKLYVVAAS 1010

  Fly   634 FTVMLSQTTFVLIVSFYFFE-----LTLVGNIWLVVALCILNGLCGMSFGFVIS------CAVDT 687
            |..:.:.||...:.:...:.     ||||.|:       :...|.|.:.....:      .|::.
Mouse  1011 FEDVNNHTTVKALFNNQAYHSPSLALTLVDNL-------LFKLLSGANASITTTNYPQPQTAIEV 1068

  Fly   688 ERTATYVA-MGSFLPIVMLCGIIWPIEGMFPLLQFFTAFLPLTKPTESMRS-ILQRGWGIDNPVV 750
            ..:..|.. .|.:|.:..|.||.:          ..::|..||...:|::| .||...|:...|.
Mouse  1069 SESILYQGPKGHYLVVNFLFGIAF----------LSSSFSILTVGEKSVKSKSLQFVSGVSTAVF 1123

  Fly   751 YNGFISISSWVLV-FLVLTILLL 772
            :   :|...|.|: |||.|:||:
Mouse  1124 W---LSALLWDLISFLVPTLLLV 1143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	80/264 (30%)
		YadH	578..773	CDD:440604	47/212 (22%)
Abca17	NP_001026792.2	rim_protein	<209..1684	CDD:130324	186/803 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1681..1733