Protein Alignment osy and Abca15

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_796187.2
• Gene: Abca15 / 320631
• MGIID: 2388709
• Length: 1668
• Species: Mus musculus
• Alignment Length: 888
• Identity: 169/888 - (19%)
• Similarity: 306/888 - (34%)
• Gaps: 257/888 - (28%)

  Fly    31 RLFISQPSTLATRRQQAVCVRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLS 95
            :.|.::|:.|..    .:.::..||::..:....|.:..|::.:.:|.:..|||.:|.||:|.||
Mouse   509 KYFEAEPTDLTA----GIQIKHLHKVFQKNNTTKVAIKDLSLNLYEGQVTVLLGHNGAGKSTTLS 569

  Fly    96 CIVGRRRLNSGEIWVLGGRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDI 160
            .:.|.....|||.:|.|.........|.. .:|..||:..|:...|:.|.|.::..|..:.:...
Mouse   570 ILSGLYPPTSGEAYVHGEDISQHMDQVRN-SLGLCPQQNLLFDHLTVSEHLYFYCRIKGVPQKMY 633

  Fly   161 EDRTEFLLKLLNL-PNASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDH 224
            .:.|..:|...|| .....|.|:||||.:|::::.:||:...::.||||||.|:||..|:|.||.
Mouse   634 LEETNNMLSAFNLMEKCDAFSKSLSGGMKRKLAIIIALIGGSKVAILDEPTSGMDPASRRSTWDI 698

  Fly   225 LVDITKNGHTTVIITTHYIDEC-AQAHMIGLLRGGKMLAEESPDYLRQQYNADS----------- 277
            |....:|  .|:::||||:||. .....|.::..|.:....|..:|::.|...|
Mouse   699 LQTYKQN--RTILLTTHYMDEADVLGDRIAIMVRGTLRCCGSSVFLKRLYGVGSHLVMVKEPYCD 761

  Fly   278 --------------------------------------------------------------LED 280
                                                                          :|:
Mouse   762 IAEISKLIHSYVPTATLETNVGNELSFILPKEYTHRFEALFTALEENQENLGISSFGVSITTMEE 826

  Fly   281 VFLKLSVLQNMGKRRRSSIAQEIVEQVTVPAISNPALDMSDEQHAAEISGEFGDNISMSSAARDP 345
            ||||:|.|::         ::..:|....|::.:......|    .|.||..|
Mouse   827 VFLKVSNLED---------SKTDIEATQSPSVGSKGNKNGD----VESSGRVG------------ 866

  Fly   346 ISTTAPAAPPLPPPQEIPTSFWYNLHVMQSHHLHALIWKNFLWMMRN-VGVMLFIVGLPVVQILL 409
                   .|.....|.|..:...:|::.|   ..|:..|..::..|| .|:::.|:||.:...||
Mouse   867 -------FPTQSEDQNIVFNTGCSLYLQQ---FRAMFMKRLMYNWRNWRGILVQILGLIISTFLL 921

  Fly   410 FCYAIGHDPTGLKLAVANHEMSGEMIMEQFCPVHTGCNQTMLSCRYLDMLVKNKSMVVQYVTDDE 474
            .   ..|:....|:...|.:..|:.|:.  ..:....|.|.....:|:.::|..:..::.|..|.
Mouse   922 L---KSHEFRYKKIRQMNLDEYGQTIVP--FSIWGKSNLTSSLLTHLENMLKPGNHQLKEVQGDL 981

  Fly   475 MAYEEVRKGRAWAALVIQPNYTASLMERVEDGRYAEDGTIESSDLAVRMDWSNQQISQLLYRDLQ 539
            :.|                                    :|.:|..|.:......|..:..|...
Mouse   982 LKY------------------------------------LEGNDECVHLCVIALSIKVVANRVNL 1010

  Fly   540 YTFFNFVGDMLSDCDVNPKLGRVPVD----------------FQHPVYGYRN---PNFTDFAAPG 585
            ...||      ::...:|.|....:|                |..|....:.   |..||    |
Mouse  1011 TVLFN------NEAYHSPSLSLTVLDNILFMSLSGSDASITVFNKPQPSPQRKEWPGSTD----G 1065

  Fly   586 VILTIIFFLAVA-VTSGAMLIDRNEGMLERCLVAGITGPEIL---LSQVVTQFTVMLSQTTFVLI 646
            .|:.....|.:| :.||..::...|...:...:..::|..||   ||.:|....:......|:|:
Mouse  1066 KIVAFKIQLGMALLVSGFCILTVTERHNKTKHMQFLSGVSILVYWLSALVFDLIIFFISCCFLLV 1130

  Fly   647 VSFY---------------FFELTLVGNIWLVVAL---------------------CILNGLCGM 675
            :..|               ...|||.|  |..:.|                     |.|:|...:
Mouse  1131 MFKYCKFDIYVTDYHILDTMLILTLFG--WSAIPLTYLLSFLFSKSNSAYINLLVFCYLSGTLSL 1193

  Fly   676 SFGFVISCAVDTERTATYVAMGSFLPIVMLCGIIWPIEGMFPLLQFFTAFLPLTKPTESMRSILQ 740
            ....:|...:.|      :...|....::...:::|:..:...:..:|...     .:.|..|.|
Mouse  1194 LMDTIIEARIST------IMSNSTQTFLLNALLLFPMYNLGKCISEYTVIY-----RKKMLCIQQ 1247

  Fly   741 RG----------------WGIDNPVVYNGFISISSWVLVFLVL 767
            :.                :.:..|::....|::|....|||:|
Mouse  1248 KNALKYLNCSNKHTKKNIYSLKKPMLGKYLIAMSIAGFVFLLL 1290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	74/309 (24%)
		YadH	578..773	CDD:440604	42/246 (17%)
Abca15	NP_796187.2	rim_protein	<108..1665	CDD:130324	169/888 (19%)