Protein Alignment osy and Abca4

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_063138015.1
• Gene: Abca4 / 310836
• RGDID: 1309445
• Length: 2312
• Species: Rattus norvegicus
• Alignment Length: 964
• Identity: 187/964 - (19%)
• Similarity: 335/964 - (34%)
• Gaps: 305/964 - (31%)

  Fly    48 VCVRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLG 112
            |||:...|::.....|.|  |.||:|..:..|...||.:|.||||.||.:.|.....||.: ::|
  Rat   929 VCVKNLVKVFEPGSRPAV--DRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTV-LIG 990

  Fly   113 GRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNLPN-A 176
            |:............:|..||...|:...|:.|.::::..:...|..:.....|.:|:...|.: .
  Rat   991 GKDIEISLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEARLEMEAMLEDTGLHHKR 1055

  Fly   177 SKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTH 241
            ::..::||||.||::|:|:|.:.:.::::|||||.||||..|:||||.|:.. ::|. |:|::||
  Rat  1056 NEEAQDLSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKY-RSGR-TIIMSTH 1118

  Fly   242 YIDECAQAHMIG----LLRGGKMLAEESPDYLRQQYNADSLEDVFLKLSVLQ------------- 289
            ::||   |.::|    ::..|::....:|.:|:..:.......:..|:..:|
  Rat  1119 HMDE---ADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRCGCEGACSCT 1180

  Fly   290 --------------------------------------------------------NMGKRRRSS 298
                                                                    |..:|..:|
  Rat  1181 SKGFSARCPARVDEITEEQVLDGDVKELTDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYAS 1245

  Fly   299 IAQEIVEQVTVPAISNPALDMSDE--------------------------------QHAAEISGE 331
            :.:|:.|  |:..:...:..:||.                                :|......|
  Rat  1246 LFRELEE--TLADLGLSSFGISDTPLEEIFLKVTEDSESGSKFVGGTQQKREHTGLRHPCSAPVE 1308

  Fly   332 FGDNISMSSAARDPISTTAPAAPPLPPPQE--IPTSFWYNLHVMQSHHLHALIWKNFLWMMRN-- 392
            .....:.:|....|.....|...|.|.|::  ||.:....| ::|  |:.||:.|.|...:|:
  Rat  1309 KHRQHAQASHTCSPGQVDPPKGQPSPEPEDPGIPFNTGARL-ILQ--HVQALLVKRFHHAVRSRK 1370

  Fly   393 --------------VGVMLFIVGLPVVQ---ILLFCYAIGHDPTGLKLAVANHE----------- 429
                          :.:||.|:..|..:   :.|..:..||..|...:...|:|
  Rat  1371 DFVAQIVLPATFVFLALMLSIIVPPFGEFPALTLHPWMYGHQFTFFSMDEPNNEHLEVLADVLLN 1435

  Fly   430 ---MSGEMIMEQFCPVHTGCNQT-----MLSCRYLDMLVKNKSMVVQYVTDDEMAYEEVRKGRAW 486
               .....:.|::.|.:...|.|     .:|.....:..|.|                      |
  Rat  1436 RPGFGNRCLKEEWLPEYPCGNATSWKTPSVSPNITHLFQKQK----------------------W 1478

  Fly   487 AALVIQPNYTASLMERV--------EDGRYAEDGTIESSDLAVRMDWSNQQISQLLYR------- 536
            .|....|....|..|::        ..|.......|:.| ..|..|.:|:.||..|.:
  Rat  1479 TAAHPSPACKCSTREKLIMLPECPEGAGGLPPPQRIQRS-TEVLQDLTNRNISDYLVKTYPALIR 1542

  Fly   537 -DLQYTFF--------NFVGDMLSDCDVNPK--------LGRVPVDFQHPVYGYRNPNFTDF--- 581
             .|:..|:        ..:|..|.|..::.:        ||::......||....:....||
  Rat  1543 SSLKSKFWVNEQRYGGISIGGKLPDIPISGEALVGFLSDLGQMMNVSGGPVTRESSREMLDFLKH 1607

  Fly   582 --AAPGVIL--------TIIFFLAV---AVTSGAMLIDRNEGMLERCLVAGITGPEILLSQVVTQ 633
              ....:.:        .::.||.|   |:...::..||:.   |...:..|:.|..|..:.:::
  Rat  1608 LETKDNIKVWFNNKGWHALVSFLNVAHNAILRASLPKDRDP---EEYGITVISQPLNLTKEQLSE 1669

  Fly   634 FTVMLSQTTFVLIVSFYF--------FELTLVGN------------------------IWLVVAL 666
            .||:.:....|:.:...|        |.|.|:..                        :|.::..
  Rat  1670 ITVLTTSIDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWMTNFLWDIMNY 1734

  Fly   667 CILNGL-CGMSFGFVISCAVDTERTATYVAMGSFLPIVMLCGIIWP-IEGMFPLLQFF----TAF 725
            .:..|| .|:..||.......|:.      :.:.:.::||.|  |. |..|:|....|    ||:
  Rat  1735 AVSAGLVVGIFIGFQKKAYTSTDN------LPALVTLLMLYG--WAVIPMMYPASFLFDVPSTAY 1791

  Fly   726 LPLTKPTESMRSILQRGWGIDNPVVYNGFISISSWVLVFLVLTI-----LLLKF 774
            :.|:                    ..|.||.|:|..:.| ||.:     :||:|
  Rat  1792 VALS--------------------CANLFIGINSSAITF-VLELFENNRMLLRF 1824

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	69/239 (29%)
		YadH	578..773	CDD:440604	46/253 (18%)
Abca4	XP_063138015.1	None