Protein Alignment osy and ABCA3

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_001080.2
• Gene: ABCA3 / 21
• HGNCID: 33
• Length: 1704
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 93/291 - (31%)
• Similarity: 152/291 - (52%)
• Gaps: 29/291 - (9%)

  Fly    23 DLDLA-ARRRLFISQPSTLATRRQQAVCVRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGAS 86
            |.|:| .|.|:....|.:|.   ...:.::...|:| ..:.|.:.:|.|::.|.||..:||||.:
Human  1358 DQDVADERTRILAPSPDSLL---HTPLIIKELSKVY-EQRVPLLAVDRLSLAVQKGECFGLLGFN 1418

  Fly    87 GCGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGI 151
            |.||||....:.|...|.||:.:| ||...|...|....||||.||..||....|.||.|:.:..
Human  1419 GAGKTTTFKMLTGEESLTSGDAFV-GGHRISSDVGKVRQRIGYCPQFDALLDHMTGREMLVMYAR 1482

  Fly   152 ISAMSKGDIEDRTEFLLK-LLNLPNASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDP 215
            :..:.:..|....|..|: ||..|:|:|.|:..|||.:|::|..:||:.||.::.||||:.|:||
Human  1483 LRGIPERHIGACVENTLRGLLLEPHANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDP 1547

  Fly   216 VLRQSIWDHLVDITKNGHTTVIITTHYIDEC-AQAHMIGLLRGGKMLAEESPDYLRQQYNA---- 275
            |.|:.:||.:....::| ..:|||:|.::|| |....:.::..|:.....||.:|:.::.:
Human  1548 VARRLLWDTVARARESG-KAIIITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGSGYSL 1611

  Fly   276 ----------DSLED--VFLKL----SVLQN 290
                      ::||:  .|:.|    |||::
Human  1612 RAKVQSEGQQEALEEFKAFVDLTFPGSVLED 1642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	82/252 (33%)
		YadH	578..773	CDD:440604
ABCA3	NP_001080.2	rim_protein	1..>43	CDD:130324
		rim_protein	<131..1699	CDD:130324	93/291 (32%)