Protein Alignment osy and abt-5

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_001364572.1
• Gene: abt-5 / 173081
• WormBaseID: WBGene00000023
• Length: 1582
• Species: Caenorhabditis elegans
• Alignment Length: 814
• Identity: 177/814 - (21%)
• Similarity: 306/814 - (37%)
• Gaps: 218/814 - (26%)

  Fly    55 KMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRG 119
            |:|   :|....::||::...:|.:..|||.:||||:|....|.|..:...|:: ::||...:..
 Worm   458 KVY---QNGEKAVNGLSLRAIRGQVSILLGHNGCGKSTTFGMITGMHQATEGKV-MIGGIDANAN 518

  Fly   120 SGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKG-DIEDRTEFLLKLLNLPN-ASKFVKN 182
            .......|||.||...:|.|.|:.|.|.....:...|.| |.:...|.|||.:.|.: .:...||
 Worm   519 RAEARELIGYCPQYNPIYDELTVWEHLRLVNALKGRSGGSDFKMDAESLLKQIELTDKRNTLAKN 583

  Fly   183 LSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTHYIDECA 247
            ||||.:|::.:.:|::....:::|||||.|:||..|..:.:.|..:  ....|:::||||:||..
 Worm   584 LSGGMKRKLCVCMAMIGGSRVILLDEPTAGMDPSARIDVQNMLALV--KADRTILLTTHYMDEAE 646

  Fly   248 Q-AHMIGLLRGGKMLAEESPDYLRQQYNA---------------------DSLEDV--------- 281
            : ...|.::..|||.|..|..||:|:|..                     ::..||
 Worm   647 KLGDWIFVMSHGKMAASGSKHYLKQKYGGGMLLTLVFKSVHDPMRPRKSYETAYDVCKTVCSTAL 711

  Fly   282 -------FLKLSVLQNMGKRRRSSIAQEIVEQVTVPAISNPAL-----DMSDEQHAAEISGEFGD 334
                   .:::|:|:.  ::.|.....:|:|.|.....:||..     |:.::....|:: ..|
 Worm   712 VKDERGQMIEISILET--EKSRLPTLLKILESVMEEDYNNPEFQALEPDIQEKCRTLELA-TIG- 772

  Fly   335 NISMSSAAR---------DPISTTAPAAPPLPPPQEIPTSFWYNLHVMQS--HHLHALIW----K 384
             :||||..:         |.|.............::..|...|.:...:.  ..|..::|    |
 Worm   773 -VSMSSLEQVFIKIGDECDDIMNGTGVDKKTERQEKFSTLVQYKIQQPKQGFSKLMMVVWALLQK 836

  Fly   385 NFLWMMRN-VGVMLFIVGLPVVQILLFCYAI--------------GHDPTG-------LKLAVAN 427
            ...::.|| |.:.|.|: ||::.:.||....              ..||:.       |:|...|
 Worm   837 RAYYLYRNPVQITLQII-LPLLTLWLFAVPFLRLEPKPPKLSDIESFDPSQYPHSTVLLQLENEN 900

  Fly   428 HEMSGEMI--MEQFCPVHTGCNQTMLSCRYLDMLVKNKSMV-------VQYVTDDEMAYEEVRKG 483
            .:.....:  ...|..|..|.|.      :...|||..|.|       |:.....:..:.::.:|
 Worm   901 DDRLANYLNSFSNFEVVKVGYND------HYGYLVKKYSQVFKTLGFIVKVNKKGDSKFYKISQG 959

  Fly   484 RAWAALVIQPNYTASLMERVEDGRYAEDGTI-ESSDLAVRMDWSNQQISQLLYRDLQYTFFNFVG 547
            ...||:::  |..||.|       |..|.:: :...:..|:.|.|.  .::.|..|. :||.|..
 Worm   960 DKNAAILM--NIIASAM-------YLRDPSVTKLPHVTSRVIWMND--PKIKYEGLA-SFFLFEN 1012

  Fly   548 DMLSDCDVNPKLGRVPVDFQHPVYGYRNPNFTDFAAPGVILTIIFFLAVA----VTSGAMLIDRN 608
                                                       ||||.|.    :.|...||:
 Worm  1013 -------------------------------------------IFFLLVLAGIFIQSTVYLIE-- 1032

  Fly   609 EGMLERCLVAGITGPEILLSQVVTQFTVMLSQTTF---VLIVSFYFFELTLVGNIWLVVALCILN 670
                           |.:......|:...||...:   |.:..|..|...|:..|..:::..:|.
 Worm  1033 ---------------EKICKFAHQQYLTGLSTIAYWGVVFLWDFLLFTFFLLYTIGFLISFGVLQ 1082

  Fly   671 G--------LCGMSFGF-----VISCAVDTERTATYVAMGSFLPIVMLCGIIWPIEGMFPLLQFF 722
            |        ..|:.|.|     :.|..::|.      ..|:|| :.|.|.|.|.   .:.::...
 Worm  1083 GHIHEIVVIFYGLLFYFAPLVYLTSALINTP------TRGNFL-LYMFCCIPWL---AYSIVSEL 1137

  Fly   723 TAFLPLTKPTESMRSILQRGWGIDNPVVYNGFIS 756
            ..|.|:.|.::.    ::.|:.|.||.:  ||::
 Worm  1138 HNFPPIQKYSDE----IEYGFRIFNPSI--GFLA 1165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	74/269 (28%)
		YadH	578..773	CDD:440604	40/199 (20%)
abt-5	NP_001364572.1	ABC2_membrane_3	<158..391	CDD:463674
		rim_protein	<419..1569	CDD:130324	177/814 (22%)