Protein Alignment osy and Eato

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_061496567.1
• Gene: Eato / 1281655
• VectorBaseID: AGAMI1_002735
• Length: 1669
• Species: Anopheles gambiae
• Alignment Length: 836
• Identity: 188/836 - (22%)
• Similarity: 332/836 - (39%)
• Gaps: 241/836 - (28%)

  Fly    45 QQAVCVRRAHKMYGSSKN-PNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEI 108
            ||.|.:....|::.|.|: ..||:....:::...||..|||.:|.||||.::.|.|.....||.|
Mosquito   501 QQVVRIANLTKVFHSRKSGAKVVVKNFGLSIYSNSITVLLGHNGAGKTTTMNIITGMVPRTSGTI 565

  Fly   109 WVLGGRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNL 173
            .|.|....:|..    .:||:.||....:...:..|.|::||.:..:.:.:.|...:.:|:.::|
Mosquito   566 VVDGEHDANRYR----HKIGFCPQHDVFFSYLSCLEHLVFFGCLRGLGRVEAEKEAKLVLEKVHL 626

  Fly   174 PNAS-KFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVI 237
            .:.| ..|..||||.:||:|||:||:...:||||||||.|:||..|:.|||.|:::.:| | ||:
Mosquito   627 LDKSDALVHTLSGGMKRRLSLAIALVGATKLLILDEPTSGLDPESRRDIWDILLNLRQN-H-TVL 689

  Fly   238 ITTHYIDECAQAHMIG----LLRGGKMLAEESPDYLRQQYNADSLEDVFLKLSVLQNMGKRRRSS 298
            :|||:::|   |.::|    ::..|:::|..||.:|:|||.    :...|||.......||....
Mosquito   690 LTTHFMEE---ADVLGDWVAIMEEGELVAFGSPLFLKQQYG----KGYTLKLLKGATFDKRETWQ 747

  Fly   299 IAQEIVEQVTVPAISNPALDMSDEQHAAEI------------------SGEFG-DNISMSSAARD 344
            ..|:::...||       .|...|..||.:                  ..|.| :.|.|::|..:
Mosquito   748 RIQQLIPNATV-------RDTVQEIFAATLPYDEIRKYAPLLKELEATQQELGIETIDMANATLE 805

  Fly   345 PI----------------------STTAPAAPPL--------PPPQEIPTSFWYNLHVMQSHHLH 379
            .:                      |.|:|||..|        |.....|          ::.:..
Mosquito   806 EVFLNSSNRRKELQHHPESVDFVDSPTSPAAENLIEIEVALHPSKLTFP----------EARNTF 860

  Fly   380 ALIW-KNFLWMMRNVGVMLFIVGLPVVQILLFCYAIGHDPTGLKLAVANHEMSGEMIMEQF--CP 441
            ..|| |.::.:..|..|..::..||.: :.:.|:.:....|....|:....::.:.|.:.|  ..
Mosquito   861 MAIWRKKWIHIKCNTHVYGWLAVLPPL-VTVLCFTLTSGITDAAKALPAVTLTADSIYQAFGVLV 924

  Fly   442 VHTG----------CNQTMLSCRYLD----MLVKNKSMV--VQYVTD-DEMAYEEVRKGRAWAAL 489
            |:.|          ..|:.|....::    ||::|.::|  :|.:.| |...|.:        .|
Mosquito   925 VNRGDRGDEFWDREAIQSDLDRHPVNGVRMMLLENYALVDALQELIDKDYTTYRD--------RL 981

  Fly   490 V--IQPNYTASLMERVEDGRYA----EDGTIESSDLAVRMDWSNQQISQLLYRDLQYTFFNFVGD 548
            |  |:.|.||       ||.:.    .:..:.|:.:|       :.::..:.  |:|    :.|:
Mosquito   982 VVGIECNVTA-------DGVHVAVLYNNNLLHSAGIA-------ETVTTTVL--LRY----YAGE 1026

  Fly   549 MLSDCDVN----PKLGRVPVDFQHPVYGYRNPNFTDFAAPGVILTIIFFLAVAVTSGAMLIDRNE 609
              :|..|:    |...:..:|.:.|.|      ||:..|......::.:|
Mosquito  1027 --ADAMVHTRNIPSTRKQLIDIKTPYY------FTELIAIAFYFYVLMYL--------------- 1068

  Fly   610 GMLERCLVAGITGPEILLSQVVTQFTVMLSQTTFVLIVSFYFFELTL-VGNIWLVVALCIL---- 669
                          ::.|.:.::.|..:.:...::...|.|.|:||: :....:|:||.:|
Mosquito  1069 --------------QVPLQEHLSGFRQLQNINRYLYWASTYAFDLTIHLAECLVVLALVLLLDRT 1119

  Fly   670 -----------------NGLCGMSFGFVISCAVDTERTATYVAMGSFLPIVMLCGIIWPIEGMFP 717
                             .|:..:...::||..||...||  :.:.|:|.||.:.|:.
Mosquito  1120 DAFTESSEREIFWTLVVYGVIALPVIYIISQCVDNANTA--ITIMSYLMIVGVGGVF-------- 1174

  Fly   718 LLQFFTAFLPLTKPTESMRSILQRGWGIDNPVVYNGFISISSWVLVFLVLTILLLK 773
                                :|..|        |:...:.|.|:.|..|:....||
Mosquito  1175 --------------------LLSNG--------YDDIKNNSGWITVLHVVPEFGLK 1202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	82/240 (34%)
		YadH	578..773	CDD:440604	34/216 (16%)
Eato	XP_061496567.1	None