DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6154 and dpep1

DIOPT Version :9

Sequence 1:	NP_651471.2	Gene:	CG6154 / 43184	FlyBaseID:	FBgn0039420	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_001307047.1	Gene:	dpep1 / 768195	ZFINID:	ZDB-GENE-061013-388	Length:	414	Species:	Danio rerio

Alignment Length:	384	Identity:	187/384 - (48%)
Similarity:	241/384 - (62%)	Gaps:	18/384 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SKTADDFDFRMQRVRNVLKEVPLIDGHNDLPWNIRKFLKNQLKDFHFGGDLRELAPWSSSAWSHT 109
            |..||:.   |.|...::.|.|||||||||||.:|....|||.|.    ||..|..      :||
Zfish    18 SSEADEL---MDRALKLMDETPLIDGHNDLPWQMRDLFNNQLNDV----DLHRLNS------THT 69

  Fly   110 DLRRLKEGMVSAQFWSAYAPCSSQHLDAVQLTLEQIDLIRRLVQLYPHHMALVTTASGIEQTHRT 174
            ::.:::.|.:|||||:|:.||.:|:.|||:.||||||:|.|:...||.......::..|......
Zfish    70 NIEKIQHGRLSAQFWAAFVPCDTQYKDAVRQTLEQIDVIHRMCDKYPDDFKFAASSQDIMDAFEQ 134

  Fly   175 GKIASLIGVEGGHAIGTSLSVLRMFYQLGARYLTLTHTCNTPWADCCKVDEPGKYPHIGGLSQFG 239
            .|.||||||||||:|.:||..||..||||.|||||||:|||||||...:|.........|||:||
Zfish   135 NKTASLIGVEGGHSIDSSLGTLRTMYQLGVRYLTLTHSCNTPWADNWLMDTESNPVRNIGLSEFG 199

  Fly   240 KLVVKEMNRLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAHAICNSSRNVPDHVLQRIAINGG 304
            |.||.||||:||::||||||...|...|..|:||:|||||||::||...|||||.||.::..|.|
Zfish   200 KQVVWEMNRIGMLIDLSHVSEKVMNQVLDISKAPIIFSHSSAYSICKHKRNVPDDVLVKVKTNRG 264

  Fly   305 LVMVAFYPHFVSCSGQATLHDVVAHINHIREVAGIDHVGIGAGYDGVNLVPKGLEDVSKYPHLFA 369
            :|||.|:..:|:|:..|||.||..|.:||::||....:|.|..||||..||.|||||||||.|..
Zfish   265 IVMVNFFNDYVTCNEHATLSDVADHFDHIKKVADASIIGFGGDYDGVPRVPVGLEDVSKYPDLVV 329

  Fly   370 ALLESDKWSEEDIAKLAGRNLIRVFKEVEAVRDQMELLRVAPIDQSIPAEDIMGRSYCR 428
            .||... ||:.:|....||||:|||::||.|||  .|....|.|:.||.:::  ::.||
Zfish   330 ELLRRG-WSDNEIKDALGRNLLRVFRDVENVRD--SLRNTKPDDKPIPLKEV--QNPCR 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6154	NP_651471.2	Peptidase_M19	61..396	CDD:395996	170/334 (51%)
dpep1	NP_001307047.1	Peptidase_M19	31..355	CDD:279569	170/334 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590328
Domainoid	1	1.000	347	1.000	Domainoid score	I1002
eggNOG	1	0.900	-	-		E1_COG2355
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80192
Inparanoid	1	1.050	348	1.000	Inparanoid score	I2265
OMA	1	1.010	-	-		QHG53057
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	1	1.000	-	-		FOG0001225
OrthoInspector	1	1.000	-	-		otm26602
orthoMCL	1	0.900	-	-		OOG6_102004
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R335
SonicParanoid	1	1.000	-	-		X677
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800