Protein Alignment E(spl)m8-HLH and hes2.1

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_001116717.2
• Gene: hes2.1 / 559147
• ZFINID: ZDB-GENE-081104-104
• Length: 195
• Species: Danio rerio
• Alignment Length: 194
• Identity: 61/194 - (31%)
• Similarity: 88/194 - (45%)
• Gaps: 53/194 - (27%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDG--ILRMDKAEMLESAVIFMRQQKTPKKVAQ 73
            :|..||::|::||||:|..|::||||:..|.|.|.  ..:::||::||..|.|:|.  .|...|:
Zfish    30 RKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTVRFLRD--LPSSSAK 92

  Fly    74 EEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEA-QSAADFIQ 137
            .:    .||:|.||...:..:|.::..:                    ||:.  || |..::|||
Zfish    93 GQ----TDSYKEGYKACLQRISTMLPQS--------------------NLET--EAHQRVSEFIQ 131

  Fly   138 NSMDCSSMD----KAPLSPASSGYHSDCDS--------------PAPS-PQPMQQ---PLWRPW 179
            .||..||..    .|..|...|..|....|              |||| |||..|   .:||||
Zfish   132 QSMASSSSSCQNCCAQNSKMISQMHQRLVSLRNNNSMENPISTVPAPSQPQPAPQAAEDMWRPW 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	25/59 (42%)
		ORANGE	81..125	CDD:128787	8/43 (19%)
hes2.1	NP_001116717.2	None