Protein Alignment E(spl)m8-HLH and her13

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_001017901.1
• Gene: her13 / 550600
• ZFINID: ZDB-GENE-050228-1
• Length: 224
• Species: Danio rerio
• Alignment Length: 211
• Identity: 53/211 - (25%)
• Similarity: 91/211 - (43%)
• Gaps: 53/211 - (25%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLE------SAVIFMRQQKTPK 69
            :|.:||::|::||||:|:.|.:|:||   |..:|...:|:.||:||      .:::..|.|:| .
Zfish    25 RKTRKPIVEKKRRARINESLQDLRTL---LTNNDLQTKMENAEVLELTVKRVESILQSRSQET-G 85

  Fly    70 KVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVM-----------THLGRVYKNL 123
            .|.||..    :.|..||:..::||...:::.||:...:...::           .||..:.|:|
Zfish    86 TVTQEAS----ERFAAGYIQCMHEVHTFVSTCPGIEARVAAELLNHLLESMPLNENHLHEMIKDL 146

  Fly   124 ----------QQFHEAQSAA------------DFIQNSMD---CSSMDKAPLSPASSGYHSDCDS 163
                      .|..|||:..            .|:.|...   ||.:|:......|:......|.
Zfish   147 ISEPSSSGDSWQSGEAQNPGRHCVSGMSSELPQFLSNPFCDDLCSDLDETETEERSASAEDTLDF 211

  Fly   164 PAPSPQPMQQPLWRPW 179
               |.....:.:||||
Zfish   212 ---SMVTHSKFMWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	23/63 (37%)
		ORANGE	81..125	CDD:128787	11/64 (17%)
her13	NP_001017901.1	bHLH_SF	23..80	CDD:469605	20/57 (35%)
		Hairy_orange	94..133	CDD:462193	7/38 (18%)