Protein Alignment E(spl)m8-HLH and Hey

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Alignment Length: 211
• Identity: 53/211 - (25%)
• Similarity: 92/211 - (43%)
• Gaps: 55/211 - (26%)

  Fly     2 EYTTKTQI-----------YQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEML 55
            |.::|.||           .:|.::.::|::||.|:|..|..||.||.......|..:::|||:|
  Fly    81 EESSKEQISPSEPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEIL 145

  Fly    56 ESAVIFMR--QQKTPKKVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVD--LGKSVMTHL 116
            :..|..::  |.||...::.:.|.:.:|....|:.....||:|.:.:..||.:.  |...:|:||
  Fly   146 QLTVEHLKSLQSKTLDSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHL 210

  Fly   117 GRVYKNLQQFHEAQSAADFIQ----NSMDCSSMDK-APLSPASSGYHSDCDS------------- 163
                    |:        |:|    ::..|:|... :|.:|:||||..:|.:
  Fly   211 --------QY--------FVQQRELSAKSCASPGGWSPAAPSSSGYQPNCAAAPYQSYAAPANPG 259

  Fly   164 ------PAPSPQPMQQ 173
                  |..|..|.||
  Fly   260 AYVSSYPTLSASPSQQ 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	20/59 (34%)
		ORANGE	81..125	CDD:128787	11/45 (24%)
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	20/67 (30%)
		ORANGE	172..218	CDD:128787	14/61 (23%)