Protein Alignment E(spl)m8-HLH and Hes6

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: XP_063123388.1
• Gene: Hes6 / 316626
• RGDID: 1312047
• Length: 234
• Species: Rattus norvegicus
• Alignment Length: 209
• Identity: 52/209 - (24%)
• Similarity: 89/209 - (42%)
• Gaps: 48/209 - (22%)

  Fly    10 YQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLESAVIFMRQQKTPKKVAQE 74
            :.:.:||::|::||||:|:.|..|:.|:|   |.:...:::.||:||..|  .|.|...:..|:|
  Rat    35 FPQARKPLVEKKRRARINESLQELRLLLA---GTEVQAKLENAEVLELTV--RRVQGALRGRARE 94

  Fly    75 EQSLPLDS---FKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADFI 136
            .:.|..::   |..||:..::||...:::...:...:...::.||    .......|..|..|.:
  Rat    95 REQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVSAELLNHL----LESMPLREGSSFRDLL 155

  Fly   137 QNSM-------DCSSMDK--APLSPASS--GYHSDCDS-------------PAPSPQPM------ 171
            .:|:       ..||...  :|.||.||  |...|..|             ||..|..:
  Rat   156 GDSLAGLPGGSGRSSWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVPTSLGI 220

  Fly   172 ------QQPLWRPW 179
                  .|.:||||
  Rat   221 LTTARRAQSVWRPW 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	20/57 (35%)
		ORANGE	81..125	CDD:128787	7/46 (15%)
Hes6	XP_063123388.1	None