Protein Alignment E(spl)m8-HLH and hes5.8

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: XP_002933896.1
• Gene: hes5.8 / 100495414
• XenbaseID: XB-GENE-22064040
• Length: 145
• Species: Xenopus tropicalis
• Alignment Length: 171
• Identity: 40/171 - (23%)
• Similarity: 70/171 - (40%)
• Gaps: 42/171 - (24%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLV-AELRGDDGILRMDKAEMLESAVIFMRQQKTPKKVAQE 74
            :|::||::|:.||.|:|..::.|:.|: .|....:...:.:||::||.||.|::|.     :|.:
 Frog    15 RKIRKPVVEKMRRDRINSSIEQLRMLLEKEFEKHNLPSKPEKADILEVAVGFLQQH-----IATK 74

  Fly    75 EQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKN-LQQFHEAQSAADFIQN 138
            ...:...|:|.||...|.:....:::              |......| |:.||..|.::.....
 Frog    75 TDEISGKSYKEGYSKCVEDSVHFLSA--------------HNQHSQGNLLRSFHGHQFSSGETHQ 125

  Fly   139 SMDCSSMDKAPLSPASSGYHSDCDSPAPSPQPMQQPLWRPW 179
            |..|...                     ||....:.|||||
 Frog   126 SRLCHGQ---------------------SPVTNSKVLWRPW 145

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	19/58 (33%)
		ORANGE	81..125	CDD:128787	8/44 (18%)
hes5.8	XP_002933896.1	bHLH-O_HES5	16..72	CDD:381467	19/60 (32%)
		Hairy_orange	81..>106	CDD:470640	6/38 (16%)