Protein Alignment E(spl)m8-HLH and hes3

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: XP_004916246.2
• Gene: hes3 / 100494165
• XenbaseID: XB-GENE-22064057
• Length: 208
• Species: Xenopus tropicalis
• Alignment Length: 204
• Identity: 55/204 - (26%)
• Similarity: 89/204 - (43%)
• Gaps: 47/204 - (23%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGI--LRMDKAEMLESAVIFMRQQKTPKKVAQ 73
            :||.||::|::||||:|..|:.||.|: |......|  .:::||::||..|.::   ||.:...|
 Frog    17 RKVSKPLMEKKRRARINVSLEQLKGLL-EKNYSQNIRKRKLEKADILELTVKYL---KTLQNSIQ 77

  Fly    74 EEQSLPLDS-FKNGYMNAVNEVSRVM--ASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSA--- 132
            ....|...: ::.|:.|.:|.|::.:  |...|.:..|.:.:...|..|  |...|....||
 Frog    78 AGNPLYRSTEYQAGFRNCLNGVNQFLLRADESGQAAHLTQDIARALPAV--NTSYFSTKDSASPP 140

  Fly   133 ----------ADFIQNSMDCSSMDKAPLSPASSGYHSDCDSP----------------APSPQ-P 170
                      |..:.||:..:...|..::|      |||..|                |||.. .
 Frog   141 ANTTPYTQILAGKMGNSVTGTQTTKRRIAP------SDCQLPTDRSSGHLAIQGHGLVAPSSNGA 199

  Fly   171 MQQPLWRPW 179
            :.|.:||||
 Frog   200 INQDVWRPW 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	23/59 (39%)
		ORANGE	81..125	CDD:128787	10/46 (22%)
hes3	XP_004916246.2	bHLH-O_HES3	24..77	CDD:381503	19/56 (34%)