Protein Alignment E(spl)m3-HLH and hey2

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_571697.2
• Gene: hey2 / 58146
• ZFINID: ZDB-GENE-000526-1
• Length: 324
• Species: Danio rerio
• Alignment Length: 285
• Identity: 67/285 - (23%)
• Similarity: 114/285 - (40%)
• Gaps: 88/285 - (30%)

  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSL 76
            ||..:.::|::||.|||..|.:|:.|:....:::|.  .:||||:||::||||::.|:..||
Zfish    49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQATGG--- 108

  Fly    77 QGVVAGVGSPPTSTSTAH---VESFRSGYVHAADQITQVLLQTQ---QTDEIGRKIMKFLST--- 132
            :|..           .||   ::....|:.....::.:.|...:   .:|.:..:::..||:
Zfish   109 KGYF-----------DAHSLAMDFLSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSSCAS 162

  Fly   133 --RLIELQTQLLQQQQQQQQH--------------QQQQIP---QSSGRLA-------------- 164
              ....:.|.:...||....|              ||..:|   .|||||:
Zfish   163 QREAAAMTTSIAHHQQALHPHHWAAALHPIPAAFLQQSGLPSSESSSGRLSEAPQRGAALFSHSD 227

  Fly   165 ----FPLLGGYGP-------------------AAAAAA----ISYSSFLTSKDELIDVTSVDGNA 202
                .|..|...|                   ||||||    :|:.:........:..:||..:.
Zfish   228 SALRAPSTGSVAPCVPPLSTSLLSLSATVHAAAAAAAAQTFPLSFPAGFPLFSPSVTASSVASST 292

  Fly   203 LS---ETASVSSQESGASEPVWRPW 224
            :|   .|::.|.|.||:|...:|||
Zfish   293 VSSSVSTSTTSQQSSGSSSKPYRPW 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	23/58 (40%)
		ORANGE	96..136	CDD:128787	5/47 (11%)
hey2	NP_571697.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		bHLH-O_HEY2	40..121	CDD:381490	28/87 (32%)
		ORANGE	119..165	CDD:128787	5/45 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	294..324		10/24 (42%)
		YRPW motif	314..317		1/2 (50%)