Protein Alignment E(spl)mbeta-HLH and hes5.2

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_001037974.1
• Gene: hes5.2 / 733755
• XenbaseID: XB-GENE-876635
• Length: 158
• Species: Xenopus tropicalis
• Alignment Length: 197
• Identity: 47/197 - (23%)
• Similarity: 85/197 - (43%)
• Gaps: 50/197 - (25%)

  Fly     3 LEMEMSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHM 67
            |:.:.....:..|:.||::|:.||.|||..:::||.:: |.:..:.:...:||||||||:||.::
 Frog     8 LDQQKMTPKEKNKLRKPVVEKMRRDRINSSIEQLKGLL-ETVFHKQQPNVKLEKADILEMTVTYL 71

  Fly    68 KKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLA---AVPGVSVDLGTQLM 129
            :    |:.|::.|   .:..:.|    |...::.||.....||...|:   ..|..:     :|:
 Frog    72 R----QQTLQIKS---EIPHNND----IQMDYKDGYSRCFEEVIDFLSLHQKQPETA-----KLI 120

  Fly   130 SHLGHRLNYLQVVVPSLPIGVPLQAPVEDQAMVTPPPSECDSLESGACSPA-PSEASSTSGPMWR 193
            ||...:.....  :.|.||                           .||.: .:..:.:|..:||
 Frog   121 SHFHSKATASS--ISSFPI---------------------------RCSQSKTANGTGSSSSLWR 156

  Fly   194 PW 195
            ||
 Frog   157 PW 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	23/67 (34%)
		ORANGE	97..141	CDD:128787	9/46 (20%)
hes5.2	NP_001037974.1	bHLH-O_HES5	20..77	CDD:381467	23/61 (38%)
		ORANGE	90..128	CDD:128787	9/42 (21%)