Protein Alignment E(spl)mdelta-HLH and hes4

DIOPT Version :10

• Sequence 1: NP_524503.2
• Gene: E(spl)mdelta-HLH / 43150
• FlyBaseID: FBgn0002734
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: NP_988870.1
• Gene: hes4 / 394465
• XenbaseID: XB-GENE-487830
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 150
• Identity: 54/150 - (36%)
• Similarity: 86/150 - (57%)
• Gaps: 15/150 - (10%)

  Fly    15 YRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVAN 79
            :||.:||::|::||||:|..|.:||.||:|.:.....:.||||||||||:||.:|:  ..|||..
 Frog    34 HRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLR--NLQRVQM 96

  Fly    80 PQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGH------QLKDMKQEEE 138
            ..:...|...|.|:|||:.:...||:...||..|::.:..|.|   |||      |:..|..::.
 Frog    97 TAALTADPSVLGKYRAGFNECMNEVTRFLSTCEGVNTEVRTRL---LGHLSSCLGQIVAMNYQQP 158

  Fly   139 IIDMAEEPVNLADQKRSKSP 158
              ..:::|:::  |..|.:|
 Frog   159 --PSSQQPLHV--QLPSSTP 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	30/61 (49%)
		ORANGE	91..135	CDD:128787	16/49 (33%)
hes4	NP_988870.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		4/9 (44%)
		bHLH-O_HES1_4	33..95	CDD:381465	31/62 (50%)
		Hairy_orange	109..147	CDD:462193	14/40 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..281
		WRPW motif. /evidence=ECO:0000255	278..281