Protein Alignment E(spl)mdelta-HLH and Hes2

DIOPT Version :10

• Sequence 1: NP_524503.2
• Gene: E(spl)mdelta-HLH / 43150
• FlyBaseID: FBgn0002734
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: NP_062109.1
• Gene: Hes2 / 29567
• RGDID: 62082
• Length: 157
• Species: Rattus norvegicus
• Alignment Length: 160
• Identity: 47/160 - (29%)
• Similarity: 77/160 - (48%)
• Gaps: 18/160 - (11%)

  Fly    16 RKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVANP 80
            ||..|||||::||||:|..|.:||.|::..:.|:..:.||||||||||:||.:|: :|...|.:.
  Rat    14 RKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLR-EQPASVCST 77

  Fly    81 QSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDMKQEEEIIDMAEE 145
            ::|.    :||.:..||......::.:......|:......|::.|..:           .::..
  Rat    78 EAPG----SLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQR-----------TVSGG 127

  Fly   146 PVNLADQKRSKSPREEDIHHGEE--VWRPW 173
            |.:|.....|.......:.....  :||||
  Rat   128 PPSLTPASASAPAPSPPVPPPSSLGLWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	31/60 (52%)
		ORANGE	91..135	CDD:128787	6/43 (14%)
Hes2	NP_062109.1	bHLH_SF	10..73	CDD:469605	31/59 (53%)
		ORANGE	84..128	CDD:128787	6/54 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		5/32 (16%)
		WRPW motif	154..157		2/2 (100%)