Protein Alignment E(spl)mdelta-HLH and Hes3

DIOPT Version :10

• Sequence 1: NP_524503.2
• Gene: E(spl)mdelta-HLH / 43150
• FlyBaseID: FBgn0002734
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: XP_011248491.1
• Gene: Hes3 / 15207
• MGIID: 104877
• Length: 291
• Species: Mus musculus
• Alignment Length: 195
• Identity: 52/195 - (26%)
• Similarity: 76/195 - (38%)
• Gaps: 54/195 - (27%)

  Fly    18 VTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVANPQS 82
            ::|||:|:|||||:|:.|::|:.|:......|..: .||||||||||:|.|:::.|..  .....
Mouse   112 ISKPLMEKKRRARINVSLEQLRSLLERHYSHQIRK-RKLEKADILELSVKYMRSLQNS--LQGLW 173

  Fly    83 PPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDMKQEEEIIDMAE--- 144
            |.|..|:   :.:|:......||.......| |......|:.|        ::|....|.|.
Mouse   174 PVPSGVD---YPSGFQGGLRGVSQRLRPGEG-DSGLRCPLLLQ--------RREGSTTDSANPQA 226

  Fly   145 ------------EPVNLADQKRS-KSP-----------------------REEDIHHGEEVWRPW 173
                        .|...|....| :||                       :.|....|..|||||
Mouse   227 TSVLNPCLPAIWAPSRAAGGSHSPQSPLPLPGGLLESSTDVVAPHPASNCQAESTRPGFRVWRPW 291

  Fly   174  173
            Mouse   292  291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	27/58 (47%)
		ORANGE	91..135	CDD:128787	7/43 (16%)
Hes3	XP_011248491.1	bHLH-O_HES3	117..171	CDD:381503	24/56 (43%)