Protein Alignment E(spl)mdelta-HLH and Hes2

DIOPT Version :10

• Sequence 1: NP_524503.2
• Gene: E(spl)mdelta-HLH / 43150
• FlyBaseID: FBgn0002734
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: NP_032262.2
• Gene: Hes2 / 15206
• MGIID: 1098624
• Length: 157
• Species: Mus musculus
• Alignment Length: 159
• Identity: 46/159 - (28%)
• Similarity: 79/159 - (49%)
• Gaps: 16/159 - (10%)

  Fly    16 RKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVANP 80
            ||..|||||::||||:|..|.:||.|::..:.|:..:.||||||||||:||.:|: :|...:.:.
Mouse    14 RKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQ-EQPATLYSS 77

  Fly    81 QSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDMKQEEEIIDMAEE 145
            .:|.|    |:.:..||......::.:......|:......|::.|  :.:.:..:...:.:...
Mouse    78 AAPGP----LNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHL--RQRTVSDDSPSLTLPPA 136

  Fly   146 PVNLADQKRSKSPREEDIHHGEE-VWRPW 173
            |        :.:|.......|.. :||||
Mouse   137 P--------APAPSPPVPPPGSSGLWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	31/60 (52%)
		ORANGE	91..135	CDD:128787	5/43 (12%)
Hes2	NP_032262.2	bHLH_SF	10..73	CDD:469605	31/59 (53%)
		ORANGE	85..123	CDD:128787	5/39 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		5/40 (13%)
		WRPW motif	154..157		2/2 (100%)