Protein Alignment CG5890 and NCS1

DIOPT Version :10

• Sequence 1: NP_001356889.1
• Gene: CG5890 / 43126
• FlyBaseID: FBgn0039380
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_055101.2
• Gene: NCS1 / 23413
• HGNCID: 3953
• Length: 190
• Species: Homo sapiens
• Alignment Length: 178
• Identity: 70/178 - (39%)
• Similarity: 114/178 - (64%)
• Gaps: 0/178 - (0%)

  Fly    26 PVALEDLCRQTKFTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKFFPHGNSSLYAHYVFKAFDV 90
            |..:|:|.|:|.||::|::..|:||..:||.|.:....|:.||.:|||.|:.:.:|.:||..||.
Human    10 PEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDE 74

  Fly    91 NCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILAIHELMGRRPHQP 155
            |.:|.|.|.:.:..||...||::.|:|||.||||||:.||.|:|.|:.:|:.||::::|.....|
Human    75 NKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELP 139

  Fly   156 EDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQMFD 203
            |::.....:|||:|..:|.|.||.:|::||.|....|..:.::|.::|
Human   140 EEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYD 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	<80..188	CDD:444056	45/107 (42%)
NCS1	NP_055101.2	FRQ1	22..174	CDD:444056	62/151 (41%)
		Interaction with IL1RAPL1. /evidence=ECO:0000269|PubMed:12783849	174..190		3/14 (21%)