Protein Alignment CG5112 and faah-3

DIOPT Version :10

• Sequence 1: NP_651400.1
• Gene: CG5112 / 43083
• FlyBaseID: FBgn0039341
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_500017.2
• Gene: faah-3 / 176916
• WormBaseID: WBGene00019068
• Length: 570
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 124/591 - (20%)
• Similarity: 220/591 - (37%)
• Gaps: 159/591 - (26%)

  Fly    19 SDRLLEFVLDWYLGEHKR--------VSGPPSLEQQTTITKSAVELAQQIRERRQRSYDIVKAYC 75
            :||.:.|  :|.....::        :|..|..|.:.::....:...:.:|..::::|
 Worm    37 ADRKINF--EWAKNSFQKLDESRAVEISAKPFEELRNSLKNGEIGPVETLRAFQRKAY------- 92

  Fly    76 ERIESVNRDLNAVVDGPFPEALDQAREIDRKLDEKEYSDEDLRRLPFLGVPFSTKDSTAVAGRLH 140
            |..|..|     .|.....|||:.|..::....:..|     ::.|..|||.|.|:|..|.....
 Worm    93 ESTEKTN-----CVCFFIQEALEIAENLEHLATDPNY-----QKPPLFGVPVSIKESIHVKNLDS 147

  Fly   141 TLGLLARKSERSTTDAECVRLMKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDLRRSVGGS 205
            |.|...:.:..|..::..|..:...||:....:|:|.........|.:.|.|.||.|..|..|||
 Worm   148 TAGYAQKINNPSDANSVSVDQLIRLGAVPFVHTNIPIALLSYGCSNGVYGTTLNPLDNSRVPGGS 212

  Fly   206 SGGEAALIAACCTGFGLGTDIGGSIRIPAFNCGIFGHKPTSGAVNMAGCTFRTGKEKDTMVCAGP 270
            |||||||::...:..|:|||:|||||.||..||:.|.|.:|......|.|......:..:...||
 Worm   213 SGGEAALVSLGGSVLGIGTDVGGSIRTPASFCGLAGFKSSSDRSPQLGKTASIPGRQLLLSVEGP 277

  Fly   271 MSRSARDLLPMMQVLVE--------PSLKAK------LKLDQKV--DLKRLRYFYVSSNGMAQCN 319
            ::::       :.|.||        |.|..|      :|..:.:  ..|.|:..|.:.:|....:
 Worm   278 IAKN-------IDVCVEYLRLKWNDPLLYKKDVYMPPVKFQENLYNSEKPLKIGYYTFDGYQTAS 335

  Fly   320 PIN----RETERVMYKIRKHFEAVSGKDVRHADLPYTKLTGKMWRYWMTQEPANFNLLLGNGAEL 380
            |..    |||..|:            |::.|..:|:.           ..:|.:...:...||
 Worm   336 PAYQRAVRETVAVL------------KELGHELVPFE-----------VPQPDHMYSIFCAGA-- 375

  Fly   381 NPFVELFKKILGQSDYSMAAIYGLIDSVLPKEK-------------EKLMRE--ATAKCKKSVQD 430
                        .:|..:..:..|.:.::|.|.             ::|:|:  ...:.::.:|:
 Worm   376 ------------TADGGLYLMDSLANDIIPPEADIGFPVAKLPHFIQRLLRKYWHHRRERQIIQE 428

  Fly   431 LLGD----------------DGVLFFHSSPRTA----------PFHYYPLVKFNDFAYFSLFNVL 469
            |..|                :.||...:....|          |.|..|.......:|.:|:|::
 Worm   429 LPHDTEEMRQMHEKIEDYRHEFVLAMRAKKLDALVCPAFGCPPPHHGMPNKILGANSYPALYNLI 493

  Fly   470 HLPATQVPMGL------------------------DSK---GMPLGIQVVANPNNDRLCLAVAEE 507
            ...|..||:.:                        :||   |:|:.:|:...|..:.:||.:.::
 Worm   494 DFAAGTVPVTVQKQEDEVELRKMKTEDSWDRRVVTESKNCIGLPVSVQIATPPYREEMCLRLLKQ 558

  Fly   508 LERTFG 513
            :|...|
 Worm   559 VEAKIG 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	GatA	50..520	CDD:439924	117/552 (21%)
faah-3	NP_500017.2	Amidase	82..553	CDD:396144	113/531 (21%)